Protein Alignment heph and Hnrnpl

DIOPT Version :9

• Sequence 1: NP_001247399.1
• Gene: heph / 48571
• FlyBaseID: FBgn0011224
• Length: 898
• Species: Drosophila melanogaster
• Sequence 2: XP_006539619.1
• Gene: Hnrnpl / 15388
• MGIID: 104816
• Length: 623
• Species: Mus musculus
• Alignment Length: 679
• Identity: 166/679 - (24%)
• Similarity: 270/679 - (39%)
• Gaps: 178/679 - (26%)

  Fly   318 KLNYLRGSDELLSQAAVMAPAS-------------DNNNQDLATKKAKLE-----------PGTV 358
            :|...:..||.|.:|..|...:             ..|....|.|:.|.|           .|:.
Mouse    15 RLEQRQQPDEQLRRAGAMVKMAAAGGGGGGGRYYGGGNEGGRAPKRLKTENAGDQHGGGGGGGSG 79

  Fly   359 LAGG----------IAKASKVIHLRNIPNESGEADVIALGIPFGRVTNVLVLKGKNQAFIEMADE 413
            .|||          ...||.|:|:|.:.:...|||::.....||.::.|:|:..|.||.:|..|.
Mouse    80 AAGGGGGENYDDPHKTPASPVVHIRGLIDGVVEADLVEALQEFGPISYVVVMPKKRQALVEFEDV 144

  Fly   414 ISATSMVSCYTVTPPQMRGRMVYVQFSNHRELKTDQGHNNSTAHSDYSVQSPASGSPLPLSAAAN 478
            :.|.:.|: |..      ...:|:           .||   .|..:||
Mouse   145 LGACNAVN-YAA------DNQIYI-----------AGH---PAFVNYS----------------- 171

  Fly   479 ATSNNANSSSDSNSAMGILQNTSAVNAGGNTNAAGGPNTVLRVIVESLMYPVSLDILHQIFQRYG 543
             ||...:...||:.:..:                   |:||...:.:.:|.::.|:|:.|....|
Mouse   172 -TSQKISRPGDSDDSRSV-------------------NSVLLFTILNPIYSITTDVLYTICNPCG 216

  Fly   544 KVLKIVTFTKNNSFQALIQYPDANSAQHAKSLLDGQNIYNGCCTLRIDNSKLTALNVKYNNDKSR 608
            .|.:||.|.| |..||::::....|||.||:.|:|.:||:|||||:|:.:|.|.|||..|:..:.
Mouse   217 PVQRIVIFRK-NGVQAMVEFDSVQSAQRAKASLNGADIYSGCCTLKIEYAKPTRLNVFKNDQDTW 280

  Fly   609 DFTNPALP-PGEPGVDIMPTAGGLMNTNDLLLIAARQR------------------PSLSVNGLG 654
            |:|||.|. .|:||          .|.|      .|||                  ||:...|..
Mouse   281 DYTNPNLSGQGDPG----------SNPN------KRQRQPPLLGDHPAEYGEGRGFPSVDSRGSC 329

  Fly   655 APGVLPPFALGLGTPL---------TGGYNNAL---------PNLAAFSLANSGALQTTAPAMRG 701
            ||...||.......||         .|||::..         |:.....:..........|:..|
Mouse   330 APARRPPRKFSPVLPLFPSHPPGGPHGGYHSHYHDEGYGPPPPHYEGRRMGPPVGGHRRGPSRYG 394

  Fly   702 --------------Y-----SNVLLVSNLNEEMVTPDALFTLFGVYGDVQRVKILYNKKDSALIQ 747
                          |     |.||:|..|::..:..|.:|.:|.:||:|::||.:.:|..:|:::
Mouse   395 PQYGHPPPPPPPPDYGPHADSPVLMVYGLDQSKMNCDRVFNVFCLYGNVEKVKFMKSKPGAAMVE 459

  Fly   748 MAEPQQAYLAMSHLDKLRLWGKPIRVMASKHQAVQLPKE--GQPDAGLT-RDYSQNPLHRFKKPG 809
            ||:......|::||:...::|:.:.|..||..|: :|.:  |..|...: :|:|::..:||..|.
Mouse   460 MADGYAVDRAITHLNNNFMFGQKMNVCVSKQPAI-MPGQSYGLEDGSCSYKDFSESRNNRFSTPE 523

  Fly   810 SKNYQNIYPPSATLHLSNIPSSCSEDDI----KEAFTSNSFEVKAFKFFPKDRKMALLQLLSVEE 870
            ......|..||..||..|.|...:|::.    .|........||.|....:.....||:..|..:
Mouse   524 QAAKNRIQHPSNVLHFFNAPLEVTEENFFEICDELGVKRPTSVKVFSGKSERSSSGLLEWDSKSD 588

  Fly   871 AVLALIKMHNHQLSESN-----HLRVSFS 894
            |:..|..::::|:...|     .|::.||
Mouse   589 ALETLGFLNHYQMKNPNGPYPYTLKLCFS 617

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
heph	NP_001247399.1	hnRNP-L_PTB	366..898	CDD:273733	151/597 (25%)
		RRM1_PTBP1_like	368..448	CDD:241132	19/79 (24%)
		RRM2_PTBP1_like	516..611	CDD:241137	38/94 (40%)
		RRM3_PTBP1_like	705..778	CDD:240869	22/72 (31%)
		RRM4_PTBP1_like	822..897	CDD:240871	19/82 (23%)
Hnrnpl	XP_006539619.1	hnRNP-L_PTB	97..621	CDD:273733	151/597 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1545178at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920