Protein Alignment heph and heph

DIOPT Version :10

• Sequence 1: NP_001247399.1
• Gene: heph / 48571
• FlyBaseID: FBgn0011224
• Length: 898
• Species: Drosophila melanogaster
• Sequence 2: XP_061506431.1
• Gene: heph / 1278776
• VectorBaseID: AGAMI1_007078
• Length: 926
• Species: Anopheles gambiae
• Alignment Length: 982
• Identity: 507/982 - (51%)
• Similarity: 586/982 - (59%)
• Gaps: 217/982 - (22%)

  Fly    34 HAPASTHPHPHPHQHPQHSAASAAAYQAMQVHQQQHQQQQQAAVFHHQVAAIAAQQQQQQQQAQV 98
            |...||.....|...|..:.||.       ::|||||||...||.....:|...........:.:
Mosquito    45 HRTTSTQLATAPPAAPVPATASL-------LYQQQHQQQPSPAVSASAPSATNVTALYAAGSSTI 102

  Fly    99 QH---------------------QQQMQQQFH-YQAQAQAQAQAMLQTYMQLQVNSAVGVSTAPA 141
            .|                     .||:....| ||.||....|...|           |:..:||
Mosquito   103 LHVELGRASTGELVSASANGLCCSQQLCYCGHCYQGQAAPPQQQQQQ-----------GIFLSPA 156

  Fly   142 TPTKPVAAQIPGAISGPIAGPVPVSVPTQFFTAPSTPLTIIPAAAVASSAMFATAATPTSAATTP 206
            .|.  :|.|               |.|.........|:.:...|.::..
Mosquito   157 APA--LATQ---------------SYPAILAQDQQHPVVVGRYADISGV---------------- 188

  Fly   207 TNNVNNTVNLSAVSRTTTTTTKKQPQAVADAVLSAVGGNVGTAVGGGTISSLLGPE-----PLPI 266
              |.|::.:.|:.|.|........|.:         .|.:|....|||.:|.....     |.|.
Mosquito   189 --NTNSSSSCSSSSTTELLNHSSSPTS---------SGEIGYYTTGGTATSTTSTPYHHAYPAPQ 242

  Fly   267 M------------PHHLP---------------LA------------------------------ 274
            :            |||||               ||
Mosquito   243 LLSHHPHHPHHPHPHHLPAHHPHPLLVQQPFQQLAHQQQQLQLYHHYHLHQQQQHQQQHQFQQQL 307

  Fly   275 -----SVRGCSSASSGCSSASSDCSMPSPTSLHLSSPKKVRIDEQYIYKLNYLRGSDELLSQAAV 334
                 |.....|.|||.|..||                          |...:||||||||||||
Mosquito   308 QQYFDSSHSSLSNSSGSSIVSS--------------------------KTLSMRGSDELLSQAAV 346

  Fly   335 MAPASDNNNQDLATKKAKLE-PGTVLAGGIAKASKVIHLRNIPNESGEADVIALGIPFGRVTNVL 398
            |||||||||||||||||||: ..||:..||.|.|:|:|:||||||..||:::.||:|||||||||
Mosquito   347 MAPASDNNNQDLATKKAKLDSTNTVIGMGITKTSRVVHIRNIPNEVSEAEIMQLGLPFGRVTNVL 411

  Fly   399 VLKGKNQAFIEMADEISATSMVSCYTVTPPQMRGRMVYVQFSNHRELKTDQGH-----NNSTAHS 458
            ||||||||||||.||.:|::|||.:...||.:|||.||||:|||||||.||.|     .|:....
Mosquito   412 VLKGKNQAFIEMGDETAASTMVSVFHANPPPLRGRTVYVQYSNHRELKIDQNHAIANVTNALQAQ 476

  Fly   459 DYSVQSPASGSPLPLSA------AANATSNNANSSSDSNSAMGILQNTSAVNAGGNTNAAGGPNT 517
            |.: ||| :|||||||.      :.||:|||.|:||.:.|:.|          ||....:|.|||
Mosquito   477 DLT-QSP-TGSPLPLSIEHTNSNSQNASSNNTNNSSTTPSSGG----------GGGGGGSGAPNT 529

  Fly   518 VLRVIVESLMYPVSLDILHQIFQRYGKVLKIVTFTKNNSFQALIQYPDANSAQHAKSLLDGQNIY 582
            |||||||||:||||||:|||||||:||||||||||||||||||||||||.:||.|::.|||||||
Mosquito   530 VLRVIVESLLYPVSLDVLHQIFQRFGKVLKIVTFTKNNSFQALIQYPDAQTAQTARASLDGQNIY 594

  Fly   583 NGCCTLRIDNSKLTALNVKYNNDKSRDFTNPALPPGEPGVDIMPTAGGLMNTNDLLLIAARQRPS 647
            |||||||||||||||||||||||||||:|||:||.||||.|::.:||||::.:||||:|..|||.
Mosquito   595 NGCCTLRIDNSKLTALNVKYNNDKSRDYTNPSLPSGEPGSDVIASAGGLVSASDLLLLATGQRPQ 659

  Fly   648 LS--------------VNGLGAPGVLPPFALGLGTP-LTGGYNNALPNLAAFSLANSGALQTTAP 697
            ||              ||||..|||:|||.|||||| |...|..|||:|.||:||::|||.|..|
Mosquito   660 LSRDRLVKLDKSPYFLVNGLATPGVMPPFGLGLGTPALASAYGGALPSLNAFALASNGALGTPNP 724

  Fly   698 A-MRGYSNVLLVSNLNEEMVTPDALFTLFGVYGDVQRVKILYNKKDSALIQMAEPQQAYLAMSHL 761
            | :||.||||||||||:||||||||||||||||||||||||||||||||||||||.||||||:||
Mosquito   725 ANVRGLSNVLLVSNLNDEMVTPDALFTLFGVYGDVQRVKILYNKKDSALIQMAEPYQAYLAMTHL 789

  Fly   762 DKLRLWGKPIRVMASKHQAVQLPKEGQPDAGLTRDYSQNPLHRFKKPGSKNYQNIYPPSATLHLS 826
            ||||:|.|.||||.||||||||||||||||||||||:||||||||||||||||||||||||||||
Mosquito   790 DKLRIWNKTIRVMPSKHQAVQLPKEGQPDAGLTRDYAQNPLHRFKKPGSKNYQNIYPPSATLHLS 854

  Fly   827 NIPSSCSEDDIKEAFTSNSFEVKAFKFFPKDRKMALLQLLSVEEAVLALIKMHNHQLSESNHLRV 891
            |||::.:||:||||||.||||||||||||||.||||:||.|:||||.|||||||:||||||||||
Mosquito   855 NIPATVTEDEIKEAFTKNSFEVKAFKFFPKDHKMALIQLSSIEEAVCALIKMHNYQLSESNHLRV 919

  Fly   892 SFSKSNI 898
            |||||||
Mosquito   920 SFSKSNI 926

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
heph	NP_001247399.1	hnRNP-L_PTB	366..898	CDD:273733	402/558 (72%)
heph	XP_061506431.1	None