Protein Alignment heph and hnrnpl

DIOPT Version :9

• Sequence 1: NP_001247399.1
• Gene: heph / 48571
• FlyBaseID: FBgn0011224
• Length: 898
• Species: Drosophila melanogaster
• Sequence 2: NP_001093751.1
• Gene: hnrnpl / 100101795
• XenbaseID: XB-GENE-491581
• Length: 538
• Species: Xenopus tropicalis
• Alignment Length: 572
• Identity: 146/572 - (25%)
• Similarity: 240/572 - (41%)
• Gaps: 131/572 - (22%)

  Fly   366 ASKVIHLRNIPNESGEADVIALGIPFGRVTNVLVLKGKNQAFIEMADEISATSMVSCYTVTPPQM 430
            ||.|:|:|.:.:...|||:......||.::.|:|:..|.||.:|..|.:.|.:.|:........:
 Frog    49 ASPVVHVRGLIDGVVEADLAEALQEFGTISYVVVMPKKRQALVEFEDILGACNAVNYAADNQIYV 113

  Fly   431 RGRMVYVQFSNHRELK--TDQGHNNSTAHSDYSVQSPASGSPLPLSAAANATSNNANSSSDSNSA 493
            .|...:|.:|..:::.  ||.|                                     .||.
 Frog   114 AGHPAFVNYSTSQKISRPTDTG-------------------------------------DDSR-- 139

  Fly   494 MGILQNTSAVNAGGNTNAAGGPNTVLRVIVESLMYPVSLDILHQIFQRYGKVLKIVTFTKNNSFQ 558
                                |.|.||...:.:.:|.::.|:|:.|....|.|.:||.|.| |..|
 Frog   140 --------------------GVNNVLLFTILNPIYSITTDVLYTICNPCGPVQRIVIFRK-NGVQ 183

  Fly   559 ALIQYPDANSAQHAKSLLDGQNIYNGCCTLRIDNSKLTALNVKYNNDKSRDFTNPALP-PGEPGV 622
            |::::....|||.||:.|:|.:||:|||||:|:.:|.:.|||..|:..:.|:|||||. .|:
 Frog   184 AMVEFDSMQSAQRAKASLNGADIYSGCCTLKIEYAKPSRLNVFKNDQDTWDYTNPALSGQGD--- 245

  Fly   623 DIMPTAGGLMNTNDLLLIAARQR--------------PSLSVNG------LGAPGVLPPF--ALG 665
                 |.|  |.|      .|||              |....:|      .|.|   ||.  :..
 Frog   246 -----AAG--NPN------KRQRNPPLLGDHPAEYGGPHAGYHGHYHEEAYGPP---PPHYESRR 294

  Fly   666 LGTPLTG----GYNNALPNLAAFSLANSGALQTTAPAMRG---YSNVLLVSNLNEEMVTPDALFT 723
            :|.|..|    |.:...|..        |......|...|   .|.||:|..|:...:..|.:|.
 Frog   295 MGPPPVGAPRRGPSRYAPQY--------GHPPPPPPPEYGPHADSPVLMVYGLDPSKMNCDRVFN 351

  Fly   724 LFGVYGDVQRVKILYNKKDSALIQMAEPQQAYLAMSHLDKLRLWGKPIRVMASKHQAVQLPKE-- 786
            :|.:||:|::||.:.:|..:|:::||:......|::||:...::|:.:.|..||.|:: :|.:
 Frog   352 VFCLYGNVEKVKFMKSKPGAAMVEMADGYAVDRAITHLNNNFMFGQKLSVCVSKQQSI-VPGQSY 415

  Fly   787 GQPDAGLT-RDYSQNPLHRFKKPGSKNYQNIYPPSATLHLSNIPSSCSEDDI----KEAFTSNSF 846
            |..|...: :.:|.:..:||..|.......|..||:.||..|.|...:|::.    .|.......
 Frog   416 GLEDGSCSFKVFSGSRNNRFTSPEQAAKNRIQQPSSVLHFFNAPPEVTEENFIEMCDELGVKKPA 480

  Fly   847 EVKAFKFFPKDRKMALLQLLSVEEAVLALIKMHNHQLSESN----HLRVSFS 894
            .:|.|....:.....||:..|..||:..|..|:::|:...:    .|::.||
 Frog   481 SIKIFSGKSERSSSGLLEWDSKSEALETLGLMNHYQMKNPSPYPYTLKLCFS 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
heph	NP_001247399.1	hnRNP-L_PTB	366..898	CDD:273733	146/572 (26%)
		RRM1_PTBP1_like	368..448	CDD:241132	20/81 (25%)
		RRM2_PTBP1_like	516..611	CDD:241137	37/94 (39%)
		RRM3_PTBP1_like	705..778	CDD:240869	22/72 (31%)
		RRM4_PTBP1_like	822..897	CDD:240871	19/81 (23%)
hnrnpl	NP_001093751.1	hnRNP-L_PTB	49..536	CDD:273733	146/572 (26%)
		RRM1_hnRNPL	49..128	CDD:241224	22/78 (28%)
		RRM2_hnRNPL	139..238	CDD:241229	39/121 (32%)
		Gly-rich_Ago1	268..>309	CDD:289530	10/43 (23%)
		RRM3_hnRNPL	333..406	CDD:241143	22/72 (31%)
		RRM_SF	449..531	CDD:302621	19/81 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1545178at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920