Protein Alignment Sam-S and SAM2

DIOPT Version :10

• Sequence 1: NP_524923.1
• Gene: Sam-S / 48552
• FlyBaseID: FBgn0005278
• Length: 408
• Species: Drosophila melanogaster
• Sequence 2: NP_010790.3
• Gene: SAM2 / 852113
• SGDID: S000002910
• Length: 384
• Species: Saccharomyces cerevisiae
• Alignment Length: 383
• Identity: 248/383 - (64%)
• Similarity: 307/383 - (80%)
• Gaps: 0/383 - (0%)

  Fly    23 MEDGATFLFTSESVGEGHPDKMCDQISDAILDAHLKQDPNAKVACETVAKTGMILLCGEITSKAV 87
            |....||||||||||||||||:|||:|||||||.|:|||.:||||||.||||||::.||||:||.
Yeast     1 MSKSKTFLFTSESVGEGHPDKICDQVSDAILDACLEQDPFSKVACETAAKTGMIMVFGEITTKAR 65

  Fly    88 VDYQKVVRETVQHIGYDDSSKGFDWKTLNLLVAIEQQSPNIANGVHINREEEDVGAGDQGIMFGY 152
            :|||::||:|::.||||||:||||:||.|:|||||||||:||.|:|..:..||:|||||||||||
Yeast    66 LDYQQIVRDTIKKIGYDDSAKGFDYKTCNVLVAIEQQSPDIAQGLHYEKSLEDLGAGDQGIMFGY 130

  Fly   153 ATDETEECMPLTVVLAHKLNEKIAELRRSDVFWWARPDSKTQVTCEYLFNQGSAVPKRVHTIVVS 217
            |||||.|.:|||::||||||..:|:.||.....|.|||:|||||.||..:.|..||||:.|:|:|
Yeast   131 ATDETPEGLPLTILLAHKLNMAMADARRDGSLPWLRPDTKTQVTVEYEDDNGRWVPKRIDTVVIS 195

  Fly   218 MQHSEKISLETLRSEVMEKVVKVVIPAKYIDANTIVHINPCGLFVIGGPMGDAGLTGRKIIVDTY 282
            .||:::||...||:::.:.:|:.|||...:|.||...|.|.|.||||||.|||||||||||||.|
Yeast   196 AQHADEISTADLRTQLQKDIVEKVIPKDMLDENTKYFIQPSGRFVIGGPQGDAGLTGRKIIVDAY 260

  Fly   283 GGWGAHGGGAFSGKDFTKVDRSAAYAARWVAKSLVKAGLCKRCLVQVSYAIGLAEPLSITVFDYG 347
            ||..:.|||||||||::||||||||||||||||||.||||||..||.|||||:|||||:.|..||
Yeast   261 GGASSVGGGAFSGKDYSKVDRSAAYAARWVAKSLVAAGLCKRVQVQFSYAIGIAEPLSLHVDTYG 325

  Fly   348 TSHKSQKELLDIIRRNFDLRPGKIVKDLNLRQPIYQRTSTYGHFGRAGFSWEEAKPLE 405
            |:.||..|:::||::|||||||.:||:|:|.:|||..|::||||....:|||:.|.||
Yeast   326 TATKSDDEIIEIIKKNFDLRPGVLVKELDLARPIYLPTASYGHFTNQEYSWEKPKKLE 383

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sam-S	NP_524923.1	S-AdoMet_synt	30..399	CDD:350837	240/368 (65%)
SAM2	NP_010790.3	S-AdoMet_synt	8..380	CDD:350837	242/371 (65%)