DRSC/TRiP Functional Genomics Resources

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Protein Alignment Sam-S and Mat1a

DIOPT Version :9

Sequence 1:NP_524923.1 Gene:Sam-S / 48552 FlyBaseID:FBgn0005278 Length:408 Species:Drosophila melanogaster
Sequence 2:NP_598414.1 Gene:Mat1a / 11720 MGIID:88017 Length:396 Species:Mus musculus


Alignment Length:381 Identity:280/381 - (73%)
Similarity:342/381 - (89%) Gaps:1/381 - (0%)


- Green bases have known domain annotations that are detailed below.


  Fly    24 EDGATFLFTSESVGEGHPDKMCDQISDAILDAHLKQDPNAKVACETVAKTGMILLCGEITSKAVV 88
            |:|| |:|||||||||||||:|||||||:||||||||||||||||||.||||:||||||||.|:|
Mouse    15 EEGA-FMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCGEITSVAMV 78

  Fly    89 DYQKVVRETVQHIGYDDSSKGFDWKTLNLLVAIEQQSPNIANGVHINREEEDVGAGDQGIMFGYA 153
            |||:|||:|::|||||||:||||:||.|:|||:|||||:||..||::|.||||||||||:|||||
Mouse    79 DYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCVHLDRNEEDVGAGDQGLMFGYA 143

  Fly   154 TDETEECMPLTVVLAHKLNEKIAELRRSDVFWWARPDSKTQVTCEYLFNQGSAVPKRVHTIVVSM 218
            |||||||||||:|||||||.:||:||||.|..|.|||||||||.:|:.:.|:.:|.|:||||:|:
Mouse   144 TDETEECMPLTIVLAHKLNTRIADLRRSGVLPWLRPDSKTQVTVQYMQDNGAVIPVRIHTIVISV 208

  Fly   219 QHSEKISLETLRSEVMEKVVKVVIPAKYIDANTIVHINPCGLFVIGGPMGDAGLTGRKIIVDTYG 283
            ||:|.|:||.::..:.|:|:|.|:||||:|.:|:.|:.|.|.||||||.||||:|||||||||||
Mouse   209 QHNEDITLEAMQEALKEQVIKAVVPAKYLDEDTVYHLQPSGRFVIGGPQGDAGVTGRKIIVDTYG 273

  Fly   284 GWGAHGGGAFSGKDFTKVDRSAAYAARWVAKSLVKAGLCKRCLVQVSYAIGLAEPLSITVFDYGT 348
            ||||||||||||||:||||||||||||||||||||||||:|.|||||||||:||||||::|.|||
Mouse   274 GWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKAGLCRRVLVQVSYAIGVAEPLSISIFTYGT 338

  Fly   349 SHKSQKELLDIIRRNFDLRPGKIVKDLNLRQPIYQRTSTYGHFGRAGFSWEEAKPL 404
            |:|:::|||:::.:|||||||.||:||:|::||||:|:.||||||:.|.||..|.|
Mouse   339 SNKTERELLEVVNKNFDLRPGVIVRDLDLKKPIYQKTACYGHFGRSEFPWEVPKKL 394

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Sam-SNP_524923.1 PTZ00104 28..408 CDD:240268 277/377 (73%)
S-AdoMet_synt_N 28..125 CDD:278846 79/96 (82%)
S-AdoMet_synt_M 140..261 CDD:280867 76/120 (63%)
S-AdoMet_synt_C 263..399 CDD:280868 106/135 (79%)
Mat1aNP_598414.1 PTZ00104 17..394 CDD:240268 278/377 (74%)
Flexible loop. /evidence=ECO:0000250|UniProtKB:P0A817 114..126 7/11 (64%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167837260
Domainoid 1 1.000 238 1.000 Domainoid score I2294
eggNOG 00.000 Not matched by this tool.
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 604 1.000 Inparanoid score I930
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG61243
OrthoDB 1 1.010 - - D357186at33208
OrthoFinder 1 1.000 - - FOG0000746
OrthoInspector 1 1.000 - - otm43992
orthoMCL 1 0.900 - - OOG6_100388
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R708
SonicParanoid 1 1.000 - - X478
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
1211.840

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