DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hrb87F and PUB1

DIOPT Version :9

Sequence 1:	NP_001163602.1	Gene:	Hrb87F / 48535	FlyBaseID:	FBgn0004237	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_014382.1	Gene:	PUB1 / 855716	SGDID:	S000004961	Length:	453	Species:	Saccharomyces cerevisiae

Alignment Length:	299	Identity:	74/299 - (24%)
Similarity:	111/299 - (37%)	Gaps:	78/299 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 AEQNDSNGNYDD-----------GEEITEPEQLRKLFIGGLDYRTTDDGLKAHFEKWGNIVDVVV 55
            :||.:.|...:|           |.|.::    |.|::|.||...|:|.||.:|:..|.|.::.:
Yeast    46 SEQAEDNQGENDPSVVPANAITGGRETSD----RVLYVGNLDKAITEDILKQYFQVGGPIANIKI 106

  Fly    56 MKDPKTKRSRGFGFITYSQSYMIDNA-QNARPHKIDGRTVEPKRAVPRQEIDSPNAGATVKKLFV 119
            |.| |..::..:.|:.|.||:..:.| |.....:|:...|:...|...|:..|.:    ...|||
Yeast   107 MID-KNNKNVNYAFVEYHQSHDANIALQTLNGKQIENNIVKINWAFQSQQSSSDD----TFNLFV 166

  Fly   120 GGLRDDHDEECLREYFKDFGQIVSVNIVSDKDTGKKRGFAFIEFDDYDPVDKIILQKTHSIKNKT 184
            |.|..:.|:|.||..||||...:|.:::.|..||..||:.|:.|...|.
Yeast   167 GDLNVNVDDETLRNAFKDFPSYLSGHVMWDMQTGSSRGYGFVSFTSQDD---------------- 215

  Fly   185 LDVKKAIAKQDMDRQGGGGGRGGP-RAGGRGGQGDRGQGGGGWGGQNRQNGGGNWGGAGGGGGFG 248
                   |:..||...|....|.| |.              .|..:...|...|:
Yeast   216 -------AQNAMDSMQGQDLNGRPLRI--------------NWAAKRDNNNNNNY---------- 249

  Fly   249 NSGGNFGGGQGGGSGGWNQQGGSGGGPWNNQGGGNGGWN 287
            ....|:|....||...:|.         ||....|.|.|
Yeast   250 QQRRNYGNNNRGGFRQYNS---------NNNNNMNMGMN 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hrb87F	NP_001163602.1	RRM1_hnRNPA_like	25..102	CDD:241022	23/77 (30%)
Hrb87F	NP_001163602.1	RRM_SF	116..188	CDD:302621	22/71 (31%)
PUB1	NP_014382.1	RRM1_PUB1	77..150	CDD:410026	22/73 (30%)
		RRM2_PUB1	161..240	CDD:410031	30/115 (26%)
		RRM3_PUB1	341..414	CDD:410033
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910