DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hrb87F and Hnrnpa0

DIOPT Version :9

Sequence 1:	NP_001163602.1	Gene:	Hrb87F / 48535	FlyBaseID:	FBgn0004237	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_084148.1	Gene:	Hnrnpa0 / 77134	MGIID:	1924384	Length:	305	Species:	Mus musculus

Alignment Length:	368	Identity:	163/368 - (44%)
Similarity:	202/368 - (54%)	Gaps:	69/368 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 EPEQLRKLFIGGLDYRTTDDGLKAHFEKWGNIVDVVVMKDPKTKRSRGFGFITYSQSYMIDNAQN 83
            |..||.|||||||:.:|::.||:.|||.:|.:.|.||:.:|:|||||.|||:|||.....|.|..
Mouse     2 ENSQLCKLFIGGLNVQTSESGLRGHFEAFGTLTDCVVVVNPQTKRSRCFGFVTYSNVEEADAAMA 66

  Fly    84 ARPHKIDGRTVEPKRAVPRQEIDSPNAGATVKKLFVGGLRDDHDEECLREYFKDFGQIVSVNIVS 148
            |.||.:||.|||.||||.|::...|.|.|.|||||||||:.|..|..|.|:|..||.:....|::
Mouse    67 ASPHAVDGNTVELKRAVSREDSARPGAHAKVKKLFVGGLKGDVAEGDLIEHFSQFGAVEKAEIIA 131

  Fly   149 DKDTGKKRGFAFIEFDDYDPVDKIILQKTHSIKNKTLDVKKAIAKQDMDRQGGGGGRGGPRAGGR 213
            ||.:||||||.|:.|..:|..||..:.|.|.|:...::||||:.|:|: ..||||.|..  .|||
Mouse   132 DKQSGKKRGFGFVYFQSHDAADKAAVVKFHPIQGHRVEVKKAVPKEDI-HAGGGGARAA--RGGR 193

  Fly   214 GGQGDRGQGGGGWGGQNRQNGGGNWGGAGGGGGFGNSGGNFGGGQGGGSGGWNQQGGSGGGPWNN 278
            |  |.||:||||.||...|||... ||.|||||: ||.|.:||           .|..|||
Mouse   194 G--GGRGRGGGGGGGGRDQNGLAK-GGGGGGGGY-NSYGGYGG-----------YGAYGGG---- 239

  Fly   279 QGGGNGGWNGGGGGGYGGGNSNGSWGGNGGGGGGGGGFG--NEYQQSYGGGPQRNSNFGNNRPAP 341
                     |||||.|||.:.          |.|.||||  :::|.|||               |
Mouse   240 ---------GGGGGSYGGSDY----------GNGFGGFGSYSQHQSSYG---------------P 270

  Fly   342 YSQGGGGGGFNKGNQGGGQGFAGNNYNTG--GGGQGGNMGGGN 382
            ...||||||   |...||:.      |:|  .||.||..|||:
Mouse   271 MKSGGGGGG---GGSWGGRS------NSGPYRGGYGGGYGGGS 304

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hrb87F	NP_001163602.1	RRM1_hnRNPA_like	25..102	CDD:241022	43/76 (57%)
Hrb87F	NP_001163602.1	RRM_SF	116..188	CDD:302621	31/71 (44%)
Hnrnpa0	NP_084148.1	RRM1_hnRNPA0	5..83	CDD:409764	43/77 (56%)
		RRM_SF	99..178	CDD:418427	36/78 (46%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	178..211		19/37 (51%)
		HnRNPA1	253..>272	CDD:402981	10/33 (30%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	265..305		23/64 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG46466
OrthoDB	1	1.010	-	-		D1202220at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.890