DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hrb87F and rbm19

DIOPT Version :9

Sequence 1:	NP_001163602.1	Gene:	Hrb87F / 48535	FlyBaseID:	FBgn0004237	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	XP_012825334.1	Gene:	rbm19 / 733862	XenbaseID:	XB-GENE-922190	Length:	920	Species:	Xenopus tropicalis

Alignment Length:	183	Identity:	51/183 - (27%)
Similarity:	75/183 - (40%)	Gaps:	49/183 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 DDGEEITEPEQLR--KLFIGGLDYRTTDDGLKAHFEKWGNIVDVVVMKDPKTKRS---RGFGFIT 71
            :|.|| .|.|.|.  .|||..|::.|:::.||..|.|.|.:....:.|......|   .||||:.
Frog   682 EDQEE-DEEEALPGCTLFIKNLNFSTSEETLKEIFSKVGAVKSCSISKKKDKSGSLLPMGFGFVE 745

  Fly    72 YSQSYMIDNAQNA----RPHKIDGRTVEPK------RAVPRQEIDSPNA---------------G 111
            |::.   :.||.|    :...:||..||.|      ||....|....|:               .
Frog   746 YTKP---EQAQKALRQLQKCTVDGHQVEIKLSERAIRAATSTERKKQNSKKQQSSKILVRNVPFQ 807

  Fly   112 ATVKKLFVGGLRDDHDEECLREYFKDFGQIVSVNIVSD-KDTGKKRGFAFIEF 163
            |||::              :||.|..||::.:|.:... ..||..|||.|::|
Frog   808 ATVRE--------------IRELFSTFGELKTVRLPKKMAGTGSHRGFGFVDF 846

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hrb87F	NP_001163602.1	RRM1_hnRNPA_like	25..102	CDD:241022	27/89 (30%)
Hrb87F	NP_001163602.1	RRM_SF	116..188	CDD:302621	13/49 (27%)
rbm19	XP_012825334.1	RRM1_RBM19	2..77	CDD:241008
		RRM2_RMB19	279..350	CDD:240946
		RRM3_RBM19	384..462	CDD:241011
		RRM4_RBM19	570..641	CDD:241013
		RRM5_RBM19_like	695..774	CDD:240764	25/81 (31%)
		RRM6_RBM19	797..875	CDD:241015	16/64 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910