DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hrb87F and hnrnpd

DIOPT Version :9

Sequence 1:	NP_001163602.1	Gene:	Hrb87F / 48535	FlyBaseID:	FBgn0004237	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_001103930.1	Gene:	hnrnpd / 560522	ZFINID:	ZDB-GENE-070424-97	Length:	314	Species:	Danio rerio

Alignment Length:	336	Identity:	111/336 - (33%)
Similarity:	167/336 - (49%)	Gaps:	58/336 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 QNDSNGNYDDGEEITEPEQLRKLFIGGLDYRTTDDGLKAHFEKWGNIVDVVVMKDPKTKRSRGFG 68
            |.::.|:..|..:..|.|  .|:|:|||.:.||...||.:|.|:|.:||..:..||.|.||||||
Zfish    36 QGEAEGSKIDASKNEEDE--GKMFVGGLSWDTTKKDLKDYFTKFGEVVDCTLKLDPLTGRSRGFG 98

  Fly    69 FITYSQSYMIDNAQNARPHKIDGRTVEPKRAVPRQEIDSPNAGATVKKLFVGGLRDDHDEECLRE 133
            |:.:.::..::.....:.||::|:.::||:| ...:...|     |||:|||||..|..||.:||
Zfish    99 FVLFKEAESVEKVITQKEHKLNGKVIDPKKA-KAMKTKEP-----VKKIFVGGLSPDTPEEKIRE 157

  Fly   134 YFKDFGQIVSVNIVSDKDTGKKRGFAFIEFDDYDPVDKIILQKTHSIKNKTLDVKKAIAKQDMDR 198
            ||..:|::.|:.:..:..|.|:|||.||.|.:.:||.||:.:..|:|.....:||.|::|:...:
Zfish   158 YFDAYGEVESIELPMENKTNKRRGFCFITFKEEEPVKKIMEKMYHNIGLSKCEVKVAMSKEQYQQ 222

  Fly   199 QGGGGGRGGPRAGGRGGQGDRGQGGGGWGGQNRQNGGGNWGGAGGGGGFGNSGGNFGGGQGGGSG 263
            |...|||||..:.|||.           ||.|:     ||     ..|:||.
Zfish   223 QQQWGGRGGYTSRGRGR-----------GGPNQ-----NW-----NQGYGNY------------- 253

  Fly   264 GWNQQGGSGGGPWNNQGGGNGGWNGGGGGGYGGGNSNGSWGGNGGGGGGGGGFGNEYQQSYGGGP 328
             |||    |.|.:.|.|..|.|:.|.||..|.|.|:.          .|.|.:.|: |..||...
Zfish   254 -WNQ----GYGNYGNYGYNNQGYGGYGGYDYSGYNNY----------YGYGDYSNQ-QSGYGKSQ 302

  Fly   329 QRNSNFGNNRP 339
            :|..:..:.:|
Zfish   303 RRGGHQNSYKP 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hrb87F	NP_001163602.1	RRM1_hnRNPA_like	25..102	CDD:241022	30/76 (39%)
Hrb87F	NP_001163602.1	RRM_SF	116..188	CDD:302621	29/71 (41%)
hnrnpd	NP_001103930.1	CBFNT	3..54	CDD:285369	5/19 (26%)
		RRM1_hnRNPD_like	56..129	CDD:241019	28/72 (39%)
		RRM2_hnRNPD	140..214	CDD:241027	31/73 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910