DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hrb87F and sart3

DIOPT Version :9

Sequence 1:	NP_001163602.1	Gene:	Hrb87F / 48535	FlyBaseID:	FBgn0004237	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_001025289.1	Gene:	sart3 / 558581	ZFINID:	ZDB-GENE-040724-10	Length:	951	Species:	Danio rerio

Alignment Length:	221	Identity:	57/221 - (25%)
Similarity:	98/221 - (44%)	Gaps:	26/221 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 PEQLRK----LFIGGLDYRTTD-DG-LKAHFEKWGNIVDVVVMKDPKTKRSRGFGFITYSQSYMI 78
            |::.||    :|:..|.:...| :| |:..|:..|.|..|..:...| ...||:.::.:.....:
Zfish   680 PKEQRKDENCVFVSNLTFNMEDPEGKLRTLFQGCGTIQQVRPVFTAK-GTFRGYCYVQFEDRLAV 743

  Fly    79 DNAQNARPHKIDGRT--VEP---KRAVPRQEIDSPNAGATVKKLFVGGLRDDHDEECLREYFKDF 138
            ..|......::|||.  |.|   |...|..::..........|:|:.||.....:|.|.:..|:.
Zfish   744 PEALKMDRQEVDGRPMYVSPCVDKNKNPDFKVFKYKTSMEKHKIFISGLPYSATKETLEDLCKEH 808

  Fly   139 GQIVSVNIVSDKDTGKKRGFAFIEFDDYDPVDKIILQKTHS-IKNKTLDVKKAIAKQDMDRQGGG 202
            |.|.::.||::: :||.:|.|::||:|.....:.:|:...: ::|.||.|  ||:.....|....
Zfish   809 GTIRAIRIVTNR-SGKSKGLAYVEFEDEAQASQAVLKMDGTMLENFTLSV--AISNPPGRRMKDE 870

  Fly   203 G------GRGGPRAGGRGGQGDRGQG 222
            .      |...||.    .||.||:|
Zfish   871 AAPSRFLGAAMPRQ----LQGARGKG 892

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hrb87F	NP_001163602.1	RRM1_hnRNPA_like	25..102	CDD:241022	20/87 (23%)
Hrb87F	NP_001163602.1	RRM_SF	116..188	CDD:302621	22/72 (31%)
sart3	NP_001025289.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..58
		RNA14	62..>496	CDD:227438
		HAT 1. /evidence=ECO:0000255	88..120
		HAT 2. /evidence=ECO:0000255	126..157
		HAT 3. /evidence=ECO:0000255	163..199
		HAT 4. /evidence=ECO:0000255	222..255
		HAT	304..336	CDD:214642
		HAT 5. /evidence=ECO:0000255	304..336
		HAT 6. /evidence=ECO:0000255	339..371
		HAT 7. /evidence=ECO:0000255	374..410
		HAT 8. /evidence=ECO:0000255	467..500
		Necessary and sufficient for U6 snRNA binding. /evidence=ECO:0000250\|UniProtKB:Q15020	517..941		57/221 (26%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	567..686		2/5 (40%)
		RRM1_SART3	689..762	CDD:240837	16/73 (22%)
		RRM	<774..919	CDD:223796	34/126 (27%)
		RRM2_SART3	783..863	CDD:240838	25/82 (30%)
		LSM_int_assoc	861..920	CDD:293211	9/36 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	905..938
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910