DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hrb87F and hnrnpa2b1

DIOPT Version :9

Sequence 1:	NP_001163602.1	Gene:	Hrb87F / 48535	FlyBaseID:	FBgn0004237	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_001192271.1	Gene:	hnrnpa2b1 / 549680	XenbaseID:	XB-GENE-490993	Length:	350	Species:	Xenopus tropicalis

Alignment Length:	375	Identity:	192/375 - (51%)
Similarity:	237/375 - (63%)	Gaps:	39/375 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 EPEQLRKLFIGGLDYRTTDDGLKAHFEKWGNIVDVVVMKDPKTKRSRGFGFITYSQSYMIDNAQN 83
            |.||.||||||||.:.||:|.|:.::|:||.:.|.|||:||.:||||||||:|:|....:|.:..
Frog     4 EKEQFRKLFIGGLSFETTEDSLRNYYEQWGKLTDCVVMRDPASKRSRGFGFVTFSSMDEVDASMA 68

  Fly    84 ARPHKIDGRTVEPKRAVPRQEIDSPNAGATVKKLFVGGLRDDHDEECLREYFKDFGQIVSVNIVS 148
            ||||.||||.|||||||.|:|...|.|..|||||||||:::|.:|..|||||:::|:|.|:.|::
Frog    69 ARPHTIDGRVVEPKRAVAREESAKPGAHVTVKKLFVGGIKEDTEEHHLREYFEEYGKIESIEIIT 133

  Fly   149 DKDTGKKRGFAFIEFDDYDPVDKIILQKTHSIKNKTLDVKKAIAKQDM-------DRQGGGGGRG 206
            ||.:||||||.|:.|||:||||||:|||.|:|.....:|:||::||:|       :.:||..|.|
Frog   134 DKQSGKKRGFGFVTFDDHDPVDKIVLQKYHTINGHNAEVRKALSKQEMQDVQNTRNSRGGNFGFG 198

  Fly   207 GPRAGGRGGQGDRGQGGGGWGGQNRQNGGGNWGGAG-GGGGFGNSGGNFGGGQGGGSGGWNQQGG 270
            ..|.||..|.|.    ||.:.|.:...|||...|.| .|.|.|.|||:||||.|.|.|    :||
Frog   199 DSRGGGNFGSGP----GGNFRGSSDGYGGGRGYGDGYNGYGGGQSGGSFGGGPGYGGG----RGG 255

  Fly   271 SGGGP-WNNQGGGNGGWNGGGGGGYGGGNSNGSWGGNGGGGGGGGGFGNEYQQSYGGGPQRN-SN 333
            .||.| :.||||      ||||||||||..|.. |||.||||....|||..|||...||.:: .|
Frog   256 YGGSPGYGNQGG------GGGGGGYGGGYDNYG-GGNYGGGGSYNDFGNYNQQSSSYGPMKSGGN 313

  Fly   334 FGNNRPAPYSQGGGGGGFNKGNQGGGQGFAGNNYNTGGGGQGGNMGGGNR 383
            ||.||    |.||..||   ||.|.|.|       :|||..||..||.||
Frog   314 FGGNR----SMGGPYGG---GNYGPGSG-------SGGGSGGGGYGGRNR 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hrb87F	NP_001163602.1	RRM1_hnRNPA_like	25..102	CDD:241022	46/76 (61%)
Hrb87F	NP_001163602.1	RRM_SF	116..188	CDD:302621	40/71 (56%)
hnrnpa2b1	NP_001192271.1	RRM1_hnRNPA2B1	7..87	CDD:241206	48/79 (61%)
		RRM2_hnRNPA2B1	100..179	CDD:241025	44/78 (56%)
		HnRNPA1	294..319	CDD:288479	13/28 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	102	1.000	Domainoid score	I6748
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	353	1.000	Inparanoid score	I2204
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1202220at2759
OrthoFinder	1	1.000	-	-		FOG0000779
OrthoInspector	1	1.000	-	-		mtm9408
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X431
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	7.060