DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hrb87F and Pabpn1

DIOPT Version :9

Sequence 1:	NP_001163602.1	Gene:	Hrb87F / 48535	FlyBaseID:	FBgn0004237	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_062275.1	Gene:	Pabpn1 / 54196	MGIID:	1859158	Length:	302	Species:	Mus musculus

Alignment Length:	86	Identity:	24/86 - (27%)
Similarity:	43/86 - (50%)	Gaps:	3/86 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 EEITEPEQLRKLFIGGLDYRTTDDGLKAHFEKWGNIVDVVVMKDPKTKRSRGFGFITYSQSYMID 79
            ||..|.: .|.:::|.:||..|.:.|:|||...|::..|.::.|..:...:||.:|.:|....:.
Mouse   160 EEKMEAD-ARSIYVGNVDYGATAEELEAHFHGCGSVNRVTILCDKFSGHPKGFAYIEFSDKESVR 223

  Fly    80 NAQNARPHKIDGRTVE--PKR 98
            .:.........||.::  |||
Mouse   224 TSLALDESLFRGRQIKVIPKR 244

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hrb87F	NP_001163602.1	RRM1_hnRNPA_like	25..102	CDD:241022	20/76 (26%)
Hrb87F	NP_001163602.1	RRM_SF	116..188	CDD:302621
Pabpn1	NP_062275.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..111
		Interaction with SKIP. /evidence=ECO:0000250	2..141
		RRM	109..>285	CDD:223796	24/86 (28%)
		Stimulates PAPOLA. /evidence=ECO:0000250	115..143
		RRM_II_PABPN1	169..244	CDD:240994	18/74 (24%)
		Strong poly(A) affinity and self-association. /evidence=ECO:0000250	255..302
		Interaction with PAPOLA. /evidence=ECO:0000250	282..302
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910