DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hrb87F and hnrnpdl

DIOPT Version :9

Sequence 1:	NP_001163602.1	Gene:	Hrb87F / 48535	FlyBaseID:	FBgn0004237	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_001011015.1	Gene:	hnrnpdl / 496424	XenbaseID:	XB-GENE-495016	Length:	297	Species:	Xenopus tropicalis

Alignment Length:	327	Identity:	102/327 - (31%)
Similarity:	150/327 - (45%)	Gaps:	58/327 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 NDSNGNYDDGEEITEPEQLRKLFIGGLDYRTTDDGLKAHFEKWGNIVDVVVMKDPKTKRSRGFGF 69
            |.|....|:|          |:|||||.:.|:...|..:..::|.:||..:..||.|.|||||||
Frog    17 NASKNQQDEG----------KMFIGGLSWDTSKKDLTEYLSRFGEVVDCTIKTDPVTGRSRGFGF 71

  Fly    70 ITYSQSYMIDNAQNARPHKIDGRTVEPKRAVPRQEIDSPNAGATVKKLFVGGLRDDHDEECLREY 134
            :.:..:..:|.....:.||:||:.::||||...:..:.|      ||:|||||..:..||.:::|
Frog    72 VLFKDAVSVDKVLETKEHKLDGKLIDPKRAKALKGKEPP------KKVFVGGLSPETTEEQIKQY 130

  Fly   135 FKDFGQIVSVNIVSDKDTGKKRGFAFIEFDDYDPVDKIILQKTHSIKNKTLDVK----KAIAKQD 195
            |..||:|.::.:..|..|.::|||.|:.:...:||.|::..:.|.|.....::|    |.:.:|.
Frog   131 FGGFGEIENIELPMDTKTNERRGFCFVTYTGEEPVKKLLESRFHQIGTGKCEIKVAQPKEVYRQQ 195

  Fly   196 MDRQGGGGGRGGPRAGGRGGQGDRGQGGGGWGGQNRQNGGGNWGGAGGGGGFGNSGGN--FGG-- 256
            ..:| ..||||.  |.||||...||: |.||..........|:|..|..|.:.:.|.|  :.|
Frog   196 QQKQ-QKGGRGA--ATGRGGARGRGR-GQGWNQGYSNYYDQNYGSYGNNGSYADQGYNNSYSGYD 256

  Fly   257 --GQGGGSGGWNQQGGSGGGPWNNQGGGNGGWNGGGGGGYGGGNSNGSWGGNGGGGGGGGGFGNE 319
              |...||.|:||                      |...|.|..|      ..|...|||...|.
Frog   257 YSGYNYGSYGYNQ----------------------GYTDYSGQQS------TYGKARGGGNHQNN 293

  Fly   320 YQ 321
            ||
Frog   294 YQ 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hrb87F	NP_001163602.1	RRM1_hnRNPA_like	25..102	CDD:241022	30/76 (39%)
Hrb87F	NP_001163602.1	RRM_SF	116..188	CDD:302621	24/71 (34%)
hnrnpdl	NP_001011015.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..21		2/3 (67%)
		RRM1_hnRPDL	27..102	CDD:410152	29/74 (39%)
		RRM2_hnRPDL	112..186	CDD:409998	25/73 (34%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	192..224		16/35 (46%)
		Trnau1ap	222..>278	CDD:407550	17/77 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910