DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hrb87F and rbm28

DIOPT Version :9

Sequence 1:	NP_001163602.1	Gene:	Hrb87F / 48535	FlyBaseID:	FBgn0004237	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_956615.1	Gene:	rbm28 / 393291	ZFINID:	ZDB-GENE-040426-960	Length:	864	Species:	Danio rerio

Alignment Length:	217	Identity:	56/217 - (25%)
Similarity:	96/217 - (44%)	Gaps:	28/217 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 EQNDSNGNYDDGEEITEPEQLRK---LFIGGLDYRTTDDGLKAHFEKWGNIVDVVVMKDPKTKRS 64
            |::..:|...:.|:|..|.:.::   |.|..|.::..||.||..|.|:|.:::..:...|..|:
Zfish   100 EESQKSGETKNTEKIPSPTKKKENSWLIIRNLSFKCEDDELKQIFSKFGTVLETRIPLKPDGKK- 163

  Fly    65 RGFGFITY--------SQSYMIDNAQNARPHKIDGRTVEPKRAVPRQEIDSPNAGATV------- 114
            :||.|:.:        :::.|...|...||.::|..|...:.|.|....:...|..|.
Zfish   164 KGFAFVQFKCVSEAEKARAAMNRKAIRDRPVEVDWTTSNTESADPEDTEEPHKAEETTSTEKFKG 228

  Fly   115 -------KKLFVGGLRDDHDEECLREYFKDFGQIVSVNIVSDKDTGKKRGFAFIEFDDYDPVDK- 171
                   .:|.:..|....:|:.|::.|.:||.::...|....| ||||||||:.|.......|
Zfish   229 IRKIKLKSRLIIRNLSFKCEEDDLKQIFSEFGTVLEAKIPLKPD-GKKRGFAFVLFKRMPEAGKA 292

  Fly   172 IILQKTHSIKNKTLDVKKAIAK 193
            :.......||::.:.|..||||
Zfish   293 LTAMNGKKIKDRQVAVDWAIAK 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hrb87F	NP_001163602.1	RRM1_hnRNPA_like	25..102	CDD:241022	22/87 (25%)
Hrb87F	NP_001163602.1	RRM_SF	116..188	CDD:302621	21/72 (29%)
rbm28	NP_956615.1	ELAV_HUD_SF	2..316	CDD:273741	56/217 (26%)
		RRM1_RBM28_like	5..77	CDD:240859
		RRM2_RBM28_like	126..198	CDD:240860	19/72 (26%)
		RRM2_RBM28_like	237..312	CDD:240860	22/75 (29%)
		RRM3_RBM28_like	438..520	CDD:240861
		RRM4_RBM28_like	590..683	CDD:240862
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910