DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hrb87F and AgaP_AGAP002374

DIOPT Version :9

Sequence 1:	NP_001163602.1	Gene:	Hrb87F / 48535	FlyBaseID:	FBgn0004237	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	XP_563821.4	Gene:	AgaP_AGAP002374 / 3290608	VectorBaseID:	AGAP002374	Length:	362	Species:	Anopheles gambiae

Alignment Length:	369	Identity:	230/369 - (62%)
Similarity:	263/369 - (71%)	Gaps:	36/369 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAEQND-SNGNYDDG----EEITEPEQLRKLFIGGLDYRTTDDGLKAHFEKWGNIVDVVVMKDPK 60
            |:|:.| .||::.:|    :||.|||.||||||||||||||||.|||:|||||.:||||||||||
Mosquito     1 MSEKQDPQNGDHQNGRNDDDEIREPEHLRKLFIGGLDYRTTDDTLKAYFEKWGKVVDVVVMKDPK 65

  Fly    61 TKRSRGFGFITYSQSYMIDNAQNARPHKIDGRTVEPKRAVPRQEIDSPNAGATVKKLFVGGLRDD 125
            |||||||||||||:|||||:||.:||||||||.||||||||||:|:.|.||::||||||||||||
Mosquito    66 TKRSRGFGFITYSKSYMIDDAQASRPHKIDGRVVEPKRAVPRQDINRPEAGSSVKKLFVGGLRDD 130

  Fly   126 HDEECLREYFKDFGQIVSVNIVSDKDTGKKRGFAFIEFDDYDPVDKIILQKTHSIKNKTLDVKKA 190
            .|||.|||||..:|.::|..||:|||.||||||.|:|||||||||||||||:|:|:||.||||||
Mosquito   131 FDEEHLREYFSKYGNVISACIVTDKDNGKKRGFGFVEFDDYDPVDKIILQKSHTIQNKLLDVKKA 195

  Fly   191 IAKQDMDRQGGGGGRGGPRAGGRGGQGDRGQGGGGWGGQNRQNGGGNWG---GAGGGGGFGNSGG 252
            :.||||||.....||.|   ||.||    |.|||.||.| |.:|||.|.   |:||||     ||
Mosquito   196 LPKQDMDRYKNDMGRTG---GGGGG----GGGGGAWGNQ-RGSGGGGWNSQRGSGGGG-----GG 247

  Fly   253 NFGGGQGGGSGGWNQQGGSGGGPWNNQGGGNGG--WNGGGGG---------GYGG-GNSNGSWGG 305
            .:|..:||.:..||..|.:.||.:||.|..|||  ||.|||.         |.|| ||:.|:|||
Mosquito   248 GWGNQRGGAANDWNSGGFNNGGGFNNGGFNNGGNNWNNGGGNPWDNGCGSQGQGGWGNNGGNWGG 312

  Fly   306 NGGGGGGGGG---FGNEYQQSYGGGPQRNSNFGNNRPAPYSQGG 346
            |.||||||.|   |||.|||.|..||.|.....|.|.|||...|
Mosquito   313 NSGGGGGGWGGNEFGNNYQQGYNAGPVRAGGNFNQRAAPYGTDG 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hrb87F	NP_001163602.1	RRM1_hnRNPA_like	25..102	CDD:241022	67/76 (88%)
Hrb87F	NP_001163602.1	RRM_SF	116..188	CDD:302621	53/71 (75%)
AgaP_AGAP002374	XP_563821.4	RRM1_hnRNPA_like	30..107	CDD:241022	67/76 (88%)
AgaP_AGAP002374	XP_563821.4	RRM2_hnRNPA_like	121..193	CDD:240774	53/71 (75%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	156	1.000	Domainoid score	I8640
eggNOG	1	0.900	-	-		E33208_3BA81
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	438	1.000	Inparanoid score	I3581
OMA	1	1.010	-	-		QHG46466
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000779
OrthoInspector	1	1.000	-	-		otm49827
Panther	1	1.100	-	-	LDO	PTHR48027
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X431
TreeFam	1	0.960	-	-
	11	10.930