DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hrb87F and hnrnpa0a

DIOPT Version :9

Sequence 1:	NP_001163602.1	Gene:	Hrb87F / 48535	FlyBaseID:	FBgn0004237	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_997810.2	Gene:	hnrnpa0a / 323529	ZFINID:	ZDB-GENE-030131-2249	Length:	305	Species:	Danio rerio

Alignment Length:	342	Identity:	157/342 - (45%)
Similarity:	206/342 - (60%)	Gaps:	51/342 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 QLRKLFIGGLDYRTTDDGLKAHFEKWGNIVDVVVMKDPKTKRSRGFGFITYSQSYMIDNAQNARP 86
            ||.|||:|||:.:||||||:.|||::|.:.|.||:::.:.||||.|||:|||.....|:|.:|||
Zfish     8 QLCKLFVGGLNVQTTDDGLRNHFEQYGKLTDCVVVQNQQLKRSRCFGFVTYSSPDEADSAMSARP 72

  Fly    87 HKIDGRTVEPKRAVPRQEIDSPNAGATVKKLFVGGLRDDHDEECLREYFKDFGQIVSVNIVSDKD 151
            |.:||..||.||||.|::...|.|.|.|||:|:|||:||.:|:.||:.|..||.:....:::||:
Zfish    73 HILDGNNVELKRAVAREDAGKPEALAKVKKIFIGGLKDDIEEDHLRDCFSQFGAVEKAEVITDKE 137

  Fly   152 TGKKRGFAFIEFDDYDPVDKIILQKTHSIKNKTLDVKKAIAKQDMDRQGG-GGGRGGPRAGGRGG 215
            |||||||.|:.|:|.|..||.::.|.|.|....::||||:.||:|...|. |||||| |.||||
Zfish   138 TGKKRGFGFVYFEDNDSADKAVVLKFHIINGHKVEVKKALTKQEMQAAGSRGGGRGG-RGGGRG- 200

  Fly   216 QGDRGQGGGGWGGQNRQNGGGNWGGAGGGGGFGNSGGNFGGGQGGGSGGWNQQGGSGGGPWNNQG 280
               .|:...|:||:              |||:||.||          ||:
Zfish   201 ---MGRPQNGYGGR--------------GGGYGNYGG----------GGY--------------- 223

  Fly   281 GGNGGWNGGGGGGYGGGNSNGSWGGNGGGGGGGGG---FGNEY-QQSYGGGPQRNSNFGNNRPAP 341
            |||.|:.||.||||||| ..|.:|....|.|||.|   ||:.| |||.|.||.: .|:.....||
Zfish   224 GGNDGYGGGYGGGYGGG-YGGGYGDQMEGYGGGNGYNDFGSGYGQQSSGYGPMK-GNYSGRSNAP 286

  Fly   342 YSQGGGGGGFNKGNQGG 358
            ||:||||||:.:|..||
Zfish   287 YSRGGGGGGYGRGGYGG 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hrb87F	NP_001163602.1	RRM1_hnRNPA_like	25..102	CDD:241022	43/76 (57%)
Hrb87F	NP_001163602.1	RRM_SF	116..188	CDD:302621	31/71 (44%)
hnrnpa0a	NP_997810.2	RRM1_hnRNPA0	8..86	CDD:240772	43/77 (56%)
		RRM_SF	102..181	CDD:302621	36/78 (46%)
		HnRNPA1	260..286	CDD:288479	10/26 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG46466
OrthoDB	1	1.010	-	-		D1202220at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	5	4.890