DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hrb87F and pabpc4

DIOPT Version :9

Sequence 1:	NP_001163602.1	Gene:	Hrb87F / 48535	FlyBaseID:	FBgn0004237	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_958453.1	Gene:	pabpc4 / 321035	ZFINID:	ZDB-GENE-030131-9663	Length:	637	Species:	Danio rerio

Alignment Length:	342	Identity:	84/342 - (24%)
Similarity:	120/342 - (35%)	Gaps:	118/342 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 RKLFIGGLDYR-------------------------TTDDGLKAHFEKWGNIVDVVVMKDPKTKR 63
            ||:|:|....|                         ..|..||..|:|:|..:.|.||.|| |.:
Zfish   167 RKVFVGRFKSRKEREAEMGAKAKEFTNVYIKNFGDDMDDQRLKELFDKYGKTLSVKVMTDP-TGK 230

  Fly    64 SRGFGFITYSQSYMIDNA-QNARPHKIDGRTVEPKRAVPRQEIDSPNAGATVKK----------- 116
            ||||||::|.:....:.| :.....:::|:||...||..:.|     ..|.:|:
Zfish   231 SRGFGFVSYEKHEDANKAVEEMNGTELNGKTVFVGRAQKKME-----RQAELKRKFEQLKQERIS 290

  Fly   117 ------LFVGGLRDDHDEECLREYFKDFGQIVSVNIVSDKDTGKKRGFAFIEFDDYDPVDKIILQ 175
                  |::..|.|..|:|.||:.|..||.|.|..::.::  |:.:||.|:.|...:...|.:.:
Zfish   291 RYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEE--GRSKGFGFVCFSSPEEATKAVTE 353

  Fly   176 KT-HSIKNKTLDV---------KKAIAKQDMDRQGG---------------GGG----------- 204
            .. ..:.:|.|.|         |..:..|.|.|..|               .||
Zfish   354 MNGRIVGSKPLYVALAQRKEERKAHLTNQYMQRIAGMRAMPANAIINQFQPAGGYFMPAVPQAQN 418

  Fly   205 -------------RGGPRAGGRGGQGDRGQGG-GGWGGQNRQNG-----------GGNWGGAGGG 244
                         |..||...:||   ||||| .|.....||.|           ..|.|..|..
Zfish   419 RTTYYAPNQLTQMRPNPRWQQQGG---RGQGGFQGMPSSLRQPGPRANIRHLAPNASNQGPRGMP 480

  Fly   245 GGFGNSGGNFGGGQGGG 261
            .|....||.   ||..|
Zfish   481 TGAQRVGGT---GQPMG 494

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hrb87F	NP_001163602.1	RRM1_hnRNPA_like	25..102	CDD:241022	29/102 (28%)
Hrb87F	NP_001163602.1	RRM_SF	116..188	CDD:302621	21/98 (21%)
pabpc4	NP_958453.1	PABP-1234	12..614	CDD:130689	84/342 (25%)
		RRM1_I_PABPs	13..92	CDD:240824
		RRM2_I_PABPs	98..173	CDD:240825	3/5 (60%)
		RRM3_I_PABPs	191..270	CDD:240826	25/79 (32%)
		RRM4_I_PABPs	294..371	CDD:240827	21/78 (27%)
		PABP	546..613	CDD:279051
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910