DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hrb87F and Rbm34

DIOPT Version :9

Sequence 1:	NP_001163602.1	Gene:	Hrb87F / 48535	FlyBaseID:	FBgn0004237	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_001014037.1	Gene:	Rbm34 / 307956	RGDID:	1310161	Length:	428	Species:	Rattus norvegicus

Alignment Length:	251	Identity:	55/251 - (21%)
Similarity:	93/251 - (37%)	Gaps:	77/251 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 QNDSNGNYDDGEEI-------------------TEPEQL---RKLFIGGLDYRTTDDGLKAHFEK 46
            ::.|.|...|||.:                   .|.|:|   |.:|:|.|........||:.|::
  Rat   141 RSQSRGKVTDGEALDVALSLNEDGRQRTKVPLNPEEERLKNERTVFVGNLPVTCNKKKLKSFFKE 205

  Fly    47 WGNIVDV---------------------------------VVMKDPKTKRSRGFGFITYSQSYMI 78
            :|.:..|                                 ||.|:.:..          :::...
  Rat   206 YGQVESVRFRSVMPAEGTLSKKLAAIKRKFHPDQKSINAYVVFKEERAA----------AKALQR 260

  Fly    79 DNAQNARPHKIDGRTVEPKRAVPRQEIDSPNAGATVKKLFVGGLRDDHDEECLREYFKDFGQIVS 143
            :.||.|...:|            |.::.|..|....:.:|||.|....||..|.|:|.|.|.||:
  Rat   261 NGAQIAEGFRI------------RVDLASETASRDKRSVFVGNLPYRVDESALEEHFLDCGSIVA 313

  Fly   144 VNIVSDKDTGKKRGFAFIEFDDYDPVDKIILQKTHSIKNKTLDVKKAIAKQDMDRQ 199
            |.||.:..||..|||.::.|::.|.|...:......:..:.|.|.:::.|:.:.:|
  Rat   314 VRIVRNPLTGVGRGFGYVLFENTDAVHLALKLNNSELMGRKLRVMRSVNKEKLKQQ 369

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hrb87F	NP_001163602.1	RRM1_hnRNPA_like	25..102	CDD:241022	15/109 (14%)
Hrb87F	NP_001163602.1	RRM_SF	116..188	CDD:302621	25/71 (35%)
Rbm34	NP_001014037.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..106
		RRM	73..364	CDD:223796	53/244 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	127..152		3/10 (30%)
		RRM1_RBM34	183..274	CDD:240840	17/112 (15%)
		RRM2_RBM34	286..358	CDD:240841	25/71 (35%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	361..428		2/9 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910