DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hrb87F and A1CF

DIOPT Version :9

Sequence 1:	NP_001163602.1	Gene:	Hrb87F / 48535	FlyBaseID:	FBgn0004237	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_001185748.1	Gene:	A1CF / 29974	HGNCID:	24086	Length:	602	Species:	Homo sapiens

Alignment Length:	168	Identity:	49/168 - (29%)
Similarity:	73/168 - (43%)	Gaps:	29/168 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 GNYDDGEEITEPEQLRKLFIGGLDYRTTDDGLKAHFEKWGNIVDVVVMKDPKTKRSRGFGFITYS 73
            |....|.:...||:..::|||.|.....:|.|....||.|.|.::.:|.| ....:||:.|:|:|
Human    49 GGPPPGWDAAPPERGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMD-FNGNNRGYAFVTFS 112

  Fly    74 QSYMIDNAQNARPHKIDGRTVEPKRAVPR---QEIDSPN-----AGATVKKLFVGGL-RDDHDEE 129
            ..                  ||.|.|:.:   .||.:..     |.....:|||||: :....||
Human   113 NK------------------VEAKNAIKQLNNYEIRNGRLLGVCASVDNCRLFVGGIPKTKKREE 159

  Fly   130 CLREYFKDFGQIVSVNIV-SDKDTGKKRGFAFIEFDDY 166
            .|.|..|....:|.|.:. |..|..|.|||||:|::.:
Human   160 ILSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESH 197

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hrb87F	NP_001163602.1	RRM1_hnRNPA_like	25..102	CDD:241022	21/76 (28%)
Hrb87F	NP_001163602.1	RRM_SF	116..188	CDD:302621	21/53 (40%)
A1CF	NP_001185748.1	hnRNP-R-Q	29..602	CDD:273732	49/168 (29%)
		RRM1_ACF	63..140	CDD:240930	23/95 (24%)
		RRM2_ACF	142..226	CDD:240934	21/56 (38%)
		RRM3_ACF	231..313	CDD:240942
		DND1_DSRM	455..531	CDD:291380
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910