DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hrb87F and PABPC1

DIOPT Version :9

Sequence 1:	NP_001163602.1	Gene:	Hrb87F / 48535	FlyBaseID:	FBgn0004237	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_002559.2	Gene:	PABPC1 / 26986	HGNCID:	8554	Length:	636	Species:	Homo sapiens

Alignment Length:	189	Identity:	50/189 - (26%)
Similarity:	93/189 - (49%)	Gaps:	20/189 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 LRK-----LFIGGLDYRTTDDGLKAHFEKWGNIVDVVVMKDPKTKRSRGFGFITYSQSYMIDNA- 81
            |||     :||..||....:..|...|..:|||:...|:.|  ...|:|:||:.:......:.|
Human    93 LRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCD--ENGSKGYGFVHFETQEAAERAI 155

  Fly    82 QNARPHKIDGRTVEPKRAVPRQEIDSPNAGATVKK---LFVGGLRDDHDEECLREYFKDFGQIVS 143
            :......::.|.|...|...|:|.:: ..||..|:   :::....:|.|:|.|::.|..||..:|
Human   156 EKMNGMLLNDRKVFVGRFKSRKEREA-ELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALS 219

  Fly   144 VNIVSDKDTGKKRGFAFIEFDDYDPVDKIILQKTHSIKNKTLDVKKAI---AKQDMDRQ 199
            |.:::| ::||.:||.|:.|:.::...|.:    ..:..|.|:.|:..   |::.::||
Human   220 VKVMTD-ESGKSKGFGFVSFERHEDAQKAV----DEMNGKELNGKQIYVGRAQKKVERQ 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hrb87F	NP_001163602.1	RRM1_hnRNPA_like	25..102	CDD:241022	20/82 (24%)
Hrb87F	NP_001163602.1	RRM_SF	116..188	CDD:302621	19/74 (26%)
PABPC1	NP_002559.2	PABP-1234	11..615	CDD:130689	50/189 (26%)
		CSDE1-binding	166..289		31/114 (27%)
		(Microbial infection) Binding to HRSV M2-1 protein. /evidence=ECO:0000269\|PubMed:31649314	541..636
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910