DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Hrb87F and Rbm45

DIOPT Version :9

Sequence 1:	NP_001163602.1	Gene:	Hrb87F / 48535	FlyBaseID:	FBgn0004237	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_695218.1	Gene:	Rbm45 / 266631	RGDID:	628862	Length:	476	Species:	Rattus norvegicus

Alignment Length:	217	Identity:	50/217 - (23%)
Similarity:	92/217 - (42%)	Gaps:	54/217 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 AEQNDSNGNYDDG-EEITEPEQLRKLFIGGLDYRTTDDGLKAHFEKWGNIVDVVVMKDPKTKRSR 65
            |..:..:|.:..| :.:.||...|...:  :...|::..|:.||..:|:|.|:.|::|..||.|:
  Rat     4 AGSSGGSGGFRPGVDSLDEPPNSRIFLV--ISKYTSESVLREHFSPFGDIQDIWVVRDKHTKESK 66

  Fly    66 GFGFITYSQSYMIDNAQNARPHKIDGRTVEPKRAVPRQEIDSPNAGATVKKLFV------GGLRD 124
            |..|:.:::|.....|.    .::.|:.:.|....|             .|:|:      |..||
  Rat    67 GIAFVKFARSSQACRAM----EEMHGQCLGPNDTKP-------------IKVFIAQSRSSGSHRD 114

  Fly   125 DHDEEC---------------LREYFKDFGQIVSVNIVSDKDTGKKRGFAFIEF----------D 164
            ..|||.               |||.||.:|.|...:::.:|.||:.:|..::.:          :
  Rat   115 VEDEELTRIFVMIPKSYTEEDLREKFKVYGDIEYCSVIKNKVTGESKGLGYVRYLKPSQAAQAIE 179

  Fly   165 DYDPVDKIILQKTHSIKNKTLD 186
            :.|...:.:|.:.   |||.|:
  Rat   180 NCDRSFRALLAEP---KNKVLE 198

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hrb87F	NP_001163602.1	RRM1_hnRNPA_like	25..102	CDD:241022	18/76 (24%)
Hrb87F	NP_001163602.1	RRM_SF	116..188	CDD:302621	25/102 (25%)
Rbm45	NP_695218.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20		3/15 (20%)
		RRM1_RBM45	23..104	CDD:240812	23/99 (23%)
		RRM2_RBM45	120..193	CDD:240813	13/75 (17%)
		RRM3_RBM45	248..320	CDD:240814
		RRM4_RBM45	393..460	CDD:240815
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910