DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hrb87F and Rbm45

DIOPT Version :9

Sequence 1:	NP_001163602.1	Gene:	Hrb87F / 48535	FlyBaseID:	FBgn0004237	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_700454.1	Gene:	Rbm45 / 241490	MGIID:	2387367	Length:	476	Species:	Mus musculus

Alignment Length:	178	Identity:	43/178 - (24%)
Similarity:	77/178 - (43%)	Gaps:	41/178 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 NGNYDDG-EEITEPEQLRKLFIGGLDYRTTDDGLKAHFEKWGNIVDVVVMKDPKTKRSRGFGFIT 71
            :|.:..| :.:.||...|...:  :...|::..|:..|..:|:|.|:.|::|..||.|:|..|:.
Mouse    10 SGGFRPGVDSLDEPPNSRIFLV--ISKHTSELVLRERFSPFGDIQDIWVVRDKHTKESKGVAFVK 72

  Fly    72 YSQSYMIDNAQNARPHKIDGRTVEPKRAVPRQEIDSPNAGATVKKLFV------GGLRDDHDEEC 130
            :::|.....|.    .::.|:.:.|....|             .|:|:      |..||..|||.
Mouse    73 FARSSQACRAM----EEMHGQCLGPSDTKP-------------IKVFIAQSRSSGSHRDVEDEEL 120

  Fly   131 ---------------LREYFKDFGQIVSVNIVSDKDTGKKRGFAFIEF 163
                           |||.||.:|.|...:|:.:|.||:.:|..::.:
Mouse   121 TRIFVMIPKSYTEEDLREKFKVYGDIEYCSIIKNKVTGESKGLGYVRY 168

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hrb87F	NP_001163602.1	RRM1_hnRNPA_like	25..102	CDD:241022	17/76 (22%)
Hrb87F	NP_001163602.1	RRM_SF	116..188	CDD:302621	20/69 (29%)
Rbm45	NP_700454.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20		2/9 (22%)
		RRM1_RBM45	23..104	CDD:240812	22/99 (22%)
		RRM2_RBM45	120..193	CDD:240813	12/49 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	192..212
		RRM3_RBM45	248..320	CDD:240814
		RRM4_RBM45	393..460	CDD:240815
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910