DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hrb87F and PUF60

DIOPT Version :9

Sequence 1:	NP_001163602.1	Gene:	Hrb87F / 48535	FlyBaseID:	FBgn0004237	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_001349824.1	Gene:	PUF60 / 22827	HGNCID:	17042	Length:	596	Species:	Homo sapiens

Alignment Length:	188	Identity:	42/188 - (22%)
Similarity:	77/188 - (40%)	Gaps:	35/188 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 KLFIGGLDYRTTDDGLKAHFEKWGNIVDVVVMKDPKTKRSRGFGFITYS------------QSYM 77
            ::::|.:.|...:|.::..|..:|.|..:.:..|..|.:.:||.|:.|.            .|.|
Human   167 RVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVM 231

  Fly    78 ID--NAQNARPHKID------GRTVEPKRAVPRQEIDSPNAGATVKKLFVGGLRDDHDEECLREY 134
            :.  |.:..||..|.      .:..|..||..|              ::|..:..|..::.::..
Human   232 LGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNR--------------IYVASVHQDLSDDDIKSV 282

  Fly   135 FKDFGQIVSVNIVSDKDTGKKRGFAFIEFDD-YDPVDKIILQKTHSIKNKTLDVKKAI 191
            |:.||:|.|..:..|..|||.:|:.|||::. ....|.:.......:..:.|.|.||:
Human   283 FEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAV 340

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hrb87F	NP_001163602.1	RRM1_hnRNPA_like	25..102	CDD:241022	21/96 (22%)
Hrb87F	NP_001163602.1	RRM_SF	116..188	CDD:302621	17/72 (24%)
PUF60	NP_001349824.1	half-pint	44..596	CDD:130706	42/188 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910