DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hrb87F and Rbmxl1

DIOPT Version :9

Sequence 1:	NP_001163602.1	Gene:	Hrb87F / 48535	FlyBaseID:	FBgn0004237	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_001239018.1	Gene:	Rbmxl1 / 19656	MGIID:	1343045	Length:	388	Species:	Mus musculus

Alignment Length:	407	Identity:	93/407 - (22%)
Similarity:	132/407 - (32%)	Gaps:	146/407 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   104 EIDSPNAGATVKKLFVGGLRDDHDEECLREYFKDFGQIVSVNIVSDKDTGKKRGFAFIEFDDYDP 168
            |.|.|.      |||:|||..:.:|:.|...|..:|:||.:.::.|::|.|.|||||:.|:  .|
Mouse     3 EADRPG------KLFIGGLNTETNEKALEAVFGKYGRIVEILLMKDRETNKSRGFAFVTFE--SP 59

  Fly   169 VDKIILQKTHSIKNKTLDVKKAIAKQDMDRQGGGGGRGGPRAGGRGGQGDRGQGGGGWGGQNRQN 233
            .|  .......:..|:|| .|||..:...:.....||.||....|.....||..||..|.:
Mouse    60 AD--AKDAARDMNGKSLD-GKAIKVEQATKPSFESGRRGPPPPPRSRGPPRGLRGGSGGTR---- 117

  Fly   234 GGGNWGGAGGGGGFGNSGG---NFGGGQGGG-----------SGGWNQQGGSGGGPWNNQGGGNG 284
                  |....||:.:.||   ||......|           |||...:..:..||..:..|..|
Mouse   118 ------GPPSRGGYMDDGGYSMNFNMSSSRGPLPVKRGPPPRSGGPPPKRSTPSGPVRSSSGMGG 176

  Fly   285 ------GWNGGGG---------------------------------------------------G 292
                  |.:..||                                                   .
Mouse   177 RTPVSRGRDSYGGPPRREPLPSRRDVYLSPRDDGYSTKDSYSSRDYPSSRDTRDYAPPPRDYTYR 241

  Fly   293 GYGGGNSNGSWGGNGGGGGGGGGFGNEYQQSYGGGPQRNS--NFGNNRPAPYSQGG----GGGGF 351
            .|...:|...:...|.|...|.|...:|.....||..|:|  ::||:|.||.::|.    ||...
Mouse   242 DYSHSSSRDDYPSRGYGDRDGYGRDRDYSDHPSGGSYRDSYESYGNSRSAPPTRGPPPSYGGSSR 306

  Fly   352 NKGNQGGGQGFAGNN----------YNTG-----------------------------------G 371
            .........|:.|:.          |::|                                   |
Mouse   307 YDDYSSSRDGYGGSRDSYSSSRSDLYSSGRDRVGRQERGLPPSMERGYPPPRDSYSSSSRGAPRG 371

  Fly   372 GGQGG---NMGGGNRRY 385
            ||:||   :.|||..||
Mouse   372 GGRGGSRSDRGGGRSRY 388

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hrb87F	NP_001163602.1	RRM1_hnRNPA_like	25..102	CDD:241022
Hrb87F	NP_001163602.1	RRM_SF	116..188	CDD:302621	26/71 (37%)
Rbmxl1	NP_001239018.1	RRM_RBMX_like	7..86	CDD:409816	30/89 (34%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	59..388		67/341 (20%)
		RBM1CTR	170..214	CDD:400429	5/43 (12%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910