DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hrb87F and RBMY1F

DIOPT Version :9

Sequence 1:	NP_001163602.1	Gene:	Hrb87F / 48535	FlyBaseID:	FBgn0004237	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_689798.1	Gene:	RBMY1F / 159163	HGNCID:	23974	Length:	496	Species:	Homo sapiens

Alignment Length:	322	Identity:	78/322 - (24%)
Similarity:	110/322 - (34%)	Gaps:	105/322 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   104 EIDSPNAGATVKKLFVGGLRDDHDEECLREYFKDFGQIVSVNIVSDKDTGKKRGFAFIEFDDYDP 168
            |.|.|.      |||:|||..:.:|:.|:..|...|.|..|.::.|: |.|.||||||.|:  :|
Human     3 EADHPG------KLFIGGLNRETNEKMLKAVFGKHGPISEVLLIKDR-TSKSRGFAFITFE--NP 58

  Fly   169 VDKIILQKTHSIKNKTLDVK------KAIAKQDMDRQG-GGGGRGGPRAGGRGGQGDRGQGGGGW 226
            .|         .||...|:.      |||..:...:.. ..|||..|.|..|
Human    59 AD---------AKNAAKDMNGTSLHGKAIKVEQAKKPSFQSGGRRRPPASSR------------- 101

  Fly   227 GGQNRQNGGGNWGGAGGGGGFGNSGGNFGGGQGGGSGGW--NQQG--GSGG-------------- 273
               ||...|..               ....|..||:.||  :.:|  ..||
Human   102 ---NRSPSGSL---------------RSARGSSGGTRGWLPSHEGHLDDGGYTPDLKMSYSRGLI 148

  Fly   274 ----GPWNNQGGGNGGWNGGGGGGYGGGNSNGSWGGNGGGGGGGGGFGNEYQQSYGGGPQRN--S 332
                ||.:..||.....:...    ....|| ||.|:.|.       .::.:::||..|:|.  |
Human   149 PVKRGPSSRSGGPPPKKSAPS----AVARSN-SWMGSQGP-------MSQRRENYGVPPRRATIS 201

  Fly   333 NFGNNRPAPYSQGGGGGGFNKGNQGGGQ----------GFAGNNYNTGGGGQGGNMGGGNRR 384
            ::.|:|   .|....|...|.||....|          |:|..:.......:..:.|..|.|
Human   202 SWRNDR---MSTRHDGYATNDGNHPSCQETRDYAPPSRGYAYRDNGHSNRDEHSSRGYRNHR 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hrb87F	NP_001163602.1	RRM1_hnRNPA_like	25..102	CDD:241022
Hrb87F	NP_001163602.1	RRM_SF	116..188	CDD:302621	27/71 (38%)
RBMY1F	NP_689798.1	RRM	<1..189	CDD:223796	60/246 (24%)
		RRM_RBMX_like	7..85	CDD:240828	31/95 (33%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	81..345		45/226 (20%)
		dnaA	158..>316	CDD:333091	26/118 (22%)
		RBM1CTR	174..218	CDD:311845	15/54 (28%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	452..496
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910