DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hrb87F and RBM45

DIOPT Version :9

Sequence 1:	NP_001163602.1	Gene:	Hrb87F / 48535	FlyBaseID:	FBgn0004237	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	XP_016858809.1	Gene:	RBM45 / 129831	HGNCID:	24468	Length:	617	Species:	Homo sapiens

Alignment Length:	310	Identity:	52/310 - (16%)
Similarity:	88/310 - (28%)	Gaps:	150/310 - (48%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 AEQNDSNGNYDDG-EEITEPEQLRKLFIGGLDYRTTDDGLKAHFEKWGNIVDVVVMKDPKTKRSR 65
            |..:.|.|.:..| :.:.||...|...:  :...|.:..|:..|..:|:|.|:.|::|..||.|:
Human     4 AGSSASGGGFRPGVDSLDEPPNSRIFLV--ISKYTPESVLRERFSPFGDIQDIWVVRDKHTKESK 66

  Fly    66 GFGFITYSQSYMIDNA-----------QNARPHKI--------------------------DGRT 93
            |..|:.:::|.....|           .:.:|.|:                          :|..
Human    67 GIAFVKFARSSQACRAMEEMHGQCLGPNDTKPIKVRVPGSGCPRGKEWASWTSLHLLLCRGEGGV 131

  Fly    94 VEPKRA------------------------------------VPRQEIDSPN--------AG--- 111
            ..|..|                                    .||:....|.        ||
Human   132 EHPFPAADQTAPGLGTGAALRRGSPPTKLRRVAGKGTGCGVFAPRERTRQPRPPGDRTAVAGLPL 196

  Fly   112 ------------------------------------------ATVKKLFV------GGLRDDHDE 128
                                                      :|..::|:      |..||..||
Human   197 SLALTNPPALEFTAKLVLAYFEYFSDLPLSDAQISIYKKRKNSTFPQVFIAQSRSSGSHRDVEDE 261

  Fly   129 EC---------------LREYFKDFGQIVSVNIVSDKDTGKKRGFAFIEF 163
            |.               |||.||.:|.|...:|:.:|.||:.:|..::.:
Human   262 ELTRIFVMIPKSYTEEDLREKFKVYGDIEYCSIIKNKVTGESKGLGYVRY 311

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hrb87F	NP_001163602.1	RRM1_hnRNPA_like	25..102	CDD:241022	20/149 (13%)
Hrb87F	NP_001163602.1	RRM_SF	116..188	CDD:302621	19/69 (28%)
RBM45	XP_016858809.1	RRM1_RBM45	23..101	CDD:409801	18/79 (23%)
		PABP-1234	<41..206	CDD:130689	24/164 (15%)
		RRM2_RBM45	263..336	CDD:409802	12/49 (24%)
		RRM3_RBM45	389..461	CDD:409803
		RRM4_RBM45	534..601	CDD:409804
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910