DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hrb87F and Sf3b4

DIOPT Version :9

Sequence 1:	NP_001163602.1	Gene:	Hrb87F / 48535	FlyBaseID:	FBgn0004237	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_694693.1	Gene:	Sf3b4 / 107701	MGIID:	109580	Length:	424	Species:	Mus musculus

Alignment Length:	193	Identity:	54/193 - (27%)
Similarity:	92/193 - (47%)	Gaps:	9/193 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 ITEPEQLRKLFIGGLDYRTTDDGLKAHFEKWGNIVDVVVMKDPKTKRSRGFGFITYSQSYMIDNA 81
            |:|..|...:::||||.:.::..|...|.:.|.:|:..:.||..|.:.:|:||:.:......|.|
Mouse     6 ISERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYA 70

  Fly    82 -QNARPHKIDGRTVEPKRAVPRQEIDSPNAGATVKKLFVGGLRDDHDEECLREYFKDFGQIVSV- 144
             :.....|:.|:.:...:|....:  :.:.||.:   |:|.|..:.||:.|.:.|..||.|:..
Mouse    71 IKIMNMIKLYGKPIRVNKASAHNK--NLDVGANI---FIGNLDPEIDEKLLYDTFSAFGVILQTP 130

  Fly   145 NIVSDKDTGKKRGFAFIEFDDYDPVDKII-LQKTHSIKNKTLDVKKAIAKQDM-DRQGGGGGR 205
            .|:.|.|||..:|:|||.|..:|..|..| ......:.|:.:.|..|..|... :|.|....|
Mouse   131 KIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYAFKKDSKGERHGSAAER 193

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hrb87F	NP_001163602.1	RRM1_hnRNPA_like	25..102	CDD:241022	19/77 (25%)
Hrb87F	NP_001163602.1	RRM_SF	116..188	CDD:302621	24/73 (33%)
Sf3b4	NP_694693.1	RRM1_SF3B4	15..88	CDD:409771	18/72 (25%)
		RRM2_SF3B4	99..181	CDD:409772	28/84 (33%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	207..424
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910