DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hrb87F and elavl4

DIOPT Version :9

Sequence 1:	NP_001163602.1	Gene:	Hrb87F / 48535	FlyBaseID:	FBgn0004237	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	XP_012815941.1	Gene:	elavl4 / 100125165	XenbaseID:	XB-GENE-948210	Length:	430	Species:	Xenopus tropicalis

Alignment Length:	238	Identity:	50/238 - (21%)
Similarity:	77/238 - (32%)	Gaps:	92/238 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 LFIGGLDYRTTDDGLKAHFEKWGNIVDVVVMKDPKTKRSRGFGFITY------------------ 72
            |::.||....|...|:..|.::|.|:...::.|..|..|||.|||.:
Frog   198 LYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKP 262

  Fly    73 ------------------------------------------SQSYMIDNAQNA-------RPHK 88
                                                      :|.:.:||..|.       .|..
Frog   263 SGAAEPITVKFANNPSQKTSQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRFSPIT 327

  Fly    89 IDGRTVEPKRAVPRQEIDSPNAGATVKKLFVGGLRDDHDEECLREYFKDFGQIVSVNIVSDKDTG 153
            |||.|       ....::.|....|...:||..|..|.||..|.:.|..||.:.:|.::.|.:|.
Frog   328 IDGMT-------SLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTN 385

  Fly   154 KKRGFAFIEFDDYDPV-------------DKII-----LQKTH 178
            |.:||.|:...:||..             |:::     ..|||
Frog   386 KCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKTH 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hrb87F	NP_001163602.1	RRM1_hnRNPA_like	25..102	CDD:241022	25/142 (18%)
Hrb87F	NP_001163602.1	RRM_SF	116..188	CDD:302621	23/81 (28%)
elavl4	XP_012815941.1	ELAV_HUD_SF	78..429	CDD:273741	50/238 (21%)
		RRM1_Hu	80..186	CDD:241094
		RRM_SF	191..280	CDD:302621	16/81 (20%)
		RRM3_HuD	344..429	CDD:241100	24/85 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910