DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Hrb87F and Gm3376

DIOPT Version :9

Sequence 1:	NP_001163602.1	Gene:	Hrb87F / 48535	FlyBaseID:	FBgn0004237	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_001257441.1	Gene:	Gm3376 / 100041505	MGIID:	3781554	Length:	380	Species:	Mus musculus

Alignment Length:	336	Identity:	76/336 - (22%)
Similarity:	115/336 - (34%)	Gaps:	102/336 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   104 EIDSPNAGATVKKLFVGGLRDDHDEECLREYFKDFGQIVSVNIVSDKDTGKKRGFAFIEFDDYDP 168
            |.|.|.      |:|:|||.....::.|:|.|..||.:..|.::.|::|.|.|||||:.|  ..|
Mouse     3 ETDQPG------KIFIGGLNIKTRQKTLQEIFGRFGPVARVILMRDRETKKSRGFAFLTF--RRP 59

  Fly   169 VD-KIILQKTHSI--KNKTLDVKKAIAKQDMDRQGGGGGRGGPRAGGRGGQGDRGQG---GGGWG 227
            .| |..:::.:.:  ..|.:.||:|.....::    .|.:..|.:..|    .||..   ..|.|
Mouse    60 ADAKNAVKEMNGVILDGKRIKVKQARRPSSLE----SGSKKRPPSFSR----TRGASRILKCGRG 116

  Fly   228 GQNRQNGG----GNWGGAGGGGGF--GNSGGNFGGGQGGGSGGWNQQGGSGGGP-----WNNQGG 281
            |::|...|    ||.||......|  .:||.:|...:       |......|.|     .:.|..
Mouse   117 GRSRARSGPSCEGNLGGDRYTPNFNVSSSGRHFAVKR-------NPSSKRDGPPSKRSATSAQTR 174

  Fly   282 GNGGWNG--------------GGGGG-----------YGGGNSNGSWGGNGGG------------ 309
            .|.|..|              |....           ||..:::..:.....|
Mouse   175 SNTGLRGREPHRREISRNMPRGEPASSRRDEYPLPRDYGQSSNDRKYESTSRGYCDYGNYHSREE 239

  Fly   310 -------------GGGGGGF-----GNEYQQSYGGGPQRNSNFGNNRPAPYSQGGGGGGFNKGNQ 356
                         ||....|     ||.|:.:|       .::|....||.::||.....:..|.
Mouse   240 SASKVFSDHAGYLGGRDRDFSEYLSGNSYRDTY-------RSYGRFHEAPSARGGNNRYDDYSNS 297

  Fly   357 GGGQGFAGNNY 367
            ..|.|..|..|
Mouse   298 QDGYGGRGEPY 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hrb87F	NP_001163602.1	RRM1_hnRNPA_like	25..102	CDD:241022
Hrb87F	NP_001163602.1	RRM_SF	116..188	CDD:302621	24/74 (32%)
Gm3376	NP_001257441.1	RRM	<3..>85	CDD:223796	29/89 (33%)
		RRM_SF	7..86	CDD:302621	28/86 (33%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	82..226		30/158 (19%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	279..358		9/30 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910