DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PpY-55A and PPT1

DIOPT Version :9

Sequence 1:	NP_001286554.1	Gene:	PpY-55A / 48532	FlyBaseID:	FBgn0003140	Length:	314	Species:	Drosophila melanogaster
Sequence 2:	NP_011639.3	Gene:	PPT1 / 853023	SGDID:	S000003355	Length:	513	Species:	Saccharomyces cerevisiae

Alignment Length:	267	Identity:	102/267 - (38%)
Similarity:	150/267 - (56%)	Gaps:	15/267 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 LKEELIERLIQQTREVIKWQPMLLELQ------APVNICGDIHGQFTDLLRIFKACG-FPPKANY 83
            |.::.:..:|.....:.:.:|.::||:      ..:::|||.||||.|:|.:|:..| ..||..|
Yeast   209 LPKKYVAAIISHADTLFRQEPSMVELENNSTPDVKISVCGDTHGQFYDVLNLFRKFGKVGPKHTY 273

  Fly    84 LFLGDYVDRGKQSLETICLLFAYKVKYPLNFFLLRGNHESASINKIYGFYDEIKRRHTVRLWHSF 148
            ||.||:||||..|.|...|.:..|:.:|.||||.||||||.::||||||.||.|.:::.|:::.|
Yeast   274 LFNGDFVDRGSWSCEVALLFYCLKILHPNNFFLNRGNHESDNMNKIYGFEDECKYKYSQRIFNMF 338

  Fly   149 TDCFNWLPVAALVGERIFCCHGGL----SPSLRNLQQINHIQRPTDIPDEGIMCDLLWADLNHTT 209
            ...|..||:|.|:.......||||    |.:|.:.:.|:...:|   |.:|...:||||| ....
Yeast   339 AQSFESLPLATLINNDYLVMHGGLPSDPSATLSDFKNIDRFAQP---PRDGAFMELLWAD-PQEA 399

  Fly   210 KGWGHNDRGVSFTFDKVIVRDFLKAFDLQLMVRAHEVVEDGYEFFANRQLVTVFSAPNYCGMMNN 274
            .|.|.:.||:...|...|...||:...|:.:.|:||:...|.:|....:|:|||||||||....|
Yeast   400 NGMGPSQRGLGHAFGPDITDRFLRNNKLRKIFRSHELRMGGVQFEQKGKLMTVFSAPNYCDSQGN 464

  Fly   275 AGGVMSV 281
            .|||:.|
Yeast   465 LGGVIHV 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PpY-55A	NP_001286554.1	PTZ00480	8..310	CDD:185658	102/267 (38%)
PpY-55A	NP_001286554.1	MPP_PP1_PPKL	8..294	CDD:277359	102/267 (38%)
PPT1	NP_011639.3	PLN03088	10..>130	CDD:215568
		TPR repeat	12..40	CDD:276809
		TPR repeat	45..75	CDD:276809
		TPR repeat	80..108	CDD:276809
		MPP_PP5_C	165..508	CDD:277362	102/267 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810