Protein Alignment PpY-55A and PPEF1

DIOPT Version :10

• Sequence 1: NP_476689.1
• Gene: PpY-55A / 48532
• FlyBaseID: FBgn0003140
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_006231.2
• Gene: PPEF1 / 5475
• HGNCID: 9243
• Length: 653
• Species: Homo sapiens
• Alignment Length: 337
• Identity: 93/337 - (27%)
• Similarity: 152/337 - (45%)
• Gaps: 62/337 - (18%)

  Fly     4 LTTHEIDCIIKELTSLNGSECTLKEELIERLIQQTREVIKWQPMLLELQA----PVNICGDIHGQ 64
            ||..:||.:::...    .:..|....:..::.:|::|:|..|....:|.    .|.||||:||:
Human   116 LTCTDIDLLLEAFK----EQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGK 176

  Fly    65 FTDLLRIFKACGFPPKAN-YLFLGDYVDRGKQSLETICLLFAYKVKYPLNFFLLRGNHESASINK 128
            ..||..||...|.|.:.| |:|.||:|||||.|:|.:.:|....:.||.:..|.|||||...:|.
Human   177 LDDLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNL 241

  Fly   129 IYGFYDEIKRR---HTVRLWHSFTDCFNWLPVAALVGERIFCCHGGLSPSLRNLQQINHIQR--- 187
            .|||..||..:   |..|:.....:.:.|||:..:|...|...|||:|.: .:|..::.::|
Human   242 RYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISET-TDLNLLHRVERNKM 305

  Fly   188 ------PTDI----------------------------PDEGI-------MCDLLWADLNHTTKG 211
                  ||:.                            |.|.:       :.|:||:|.......
Human   306 KSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIKTNGSPTEHLTEHEWEQIIDILWSDPRGKNGC 370

  Fly   212 WGHNDRGVSFTFDKVIVRDFLKAFDLQLMVRAHEVVEDGYEFFANRQLVTVFSAPNYCGMMNNAG 276
            :.:..||....|...:....|..:.|::::|:||...:|||...:.::||:|||.||....:|.|
Human   371 FPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYEEGSNRG 435

  Fly   277 GVMSVSTDLICS 288
            ..:.     :||
Human   436 AYIK-----LCS 442

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PpY-55A	NP_476689.1	MPP_PP1_PPKL	8..294	CDD:277359	91/333 (27%)
PPEF1	NP_006231.2	MPP_RdgC	115..452	CDD:277364	93/337 (28%)
		Catalytic	121..455		91/332 (27%)
		FRQ1	487..635	CDD:444056
		EF-hand_7	568..636	CDD:463900
		IQ	18..37	CDD:197470