DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment PpY-55A and Ppef1

DIOPT Version :9

Sequence 1:	NP_001286554.1	Gene:	PpY-55A / 48532	FlyBaseID:	FBgn0003140	Length:	314	Species:	Drosophila melanogaster
Sequence 2:	XP_038955765.1	Gene:	Ppef1 / 317498	RGDID:	1562772	Length:	664	Species:	Rattus norvegicus

Alignment Length:	319	Identity:	91/319 - (28%)
Similarity:	149/319 - (46%)	Gaps:	44/319 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LTTHEIDCIIKELTSLNGSECTLKEELIERLIQQTREVIKWQPMLLELQA----PVNICGDIHGQ 64
            ||..:|:.:::...    .:.||....:..::.:.|:::|..|....:|.    .:.||||:||:
  Rat   141 LTFTDINLLLQAFK----QQQTLHAHYVLEVLFEARKILKQMPNFTRIQTFPAKEITICGDLHGK 201

  Fly    65 FTDLLRIFKACGFPPKAN-YLFLGDYVDRGKQSLETICLLFAYKVKYPLNFFLLRGNHESASINK 128
            ..||:.||...|.|.:.| |:|.||:||||..|:|.:.:|....:.||.:..|.|||||...:|.
  Rat   202 LDDLMLIFYKNGLPSEKNPYVFNGDFVDRGNNSMEILMILLVSFLVYPTDLHLNRGNHEDFMMNL 266

  Fly   129 IYGFYDEIKRR---HTVRLWHSFTDCFNWLPVAALVGERIFCCHGGLSPS--LRNLQQIN----- 183
            .|||..||.::   |..::.....:.:.|||:..::...|...|||:|.|  |..|||:.
  Rat   267 RYGFTKEILQKYKLHGKKILQVLEELYTWLPIGTIIDNEILVIHGGISESTDLNILQQLQRNKMK 331

  Fly   184 -------------HIQRPTDIPDEGI------------MCDLLWADLNHTTKGWGHNDRGVSFTF 223
                         :|::....|.|..            :.||||:|.......:.:..||....|
  Rat   332 SVLMPPMSTNQECNIKKNKAGPSEQSASEQLTKLEWEQIIDLLWSDPRGKKGCYPNTSRGGGCYF 396

  Fly   224 DKVIVRDFLKAFDLQLMVRAHEVVEDGYEFFANRQLVTVFSAPNYCGMMNNAGGVMSVS 282
            ...:....|....|::::|:||...||||...:.:::|||||.||....:|.|..:.:|
  Rat   397 GPDVTSKVLNKNQLKMVIRSHECKPDGYEICHDGKVITVFSASNYYEEGSNRGAYIRLS 455

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PpY-55A	NP_001286554.1	PTZ00480	8..310	CDD:185658	89/315 (28%)
PpY-55A	NP_001286554.1	MPP_PP1_PPKL	8..294	CDD:277359	89/315 (28%)
Ppef1	XP_038955765.1	IQ	40..>57	CDD:197470
		MPP_RdgC	140..466	CDD:277364	91/319 (29%)
		PTZ00183	505..647	CDD:185503
		EF-hand_7	582..650	CDD:404394
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810