DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PpY-55A and dis2

DIOPT Version :9

Sequence 1:	NP_001286554.1	Gene:	PpY-55A / 48532	FlyBaseID:	FBgn0003140	Length:	314	Species:	Drosophila melanogaster
Sequence 2:	NP_596317.1	Gene:	dis2 / 2541193	PomBaseID:	SPBC776.02c	Length:	327	Species:	Schizosaccharomyces pombe

Alignment Length:	294	Identity:	181/294 - (61%)
Similarity:	223/294 - (75%)	Gaps:	4/294 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 EIDCIIKELTSLNGS----ECTLKEELIERLIQQTREVIKWQPMLLELQAPVNICGDIHGQFTDL 68
            ::|.||..|..:.||    :..|.|:.|..|..:.||:...||:||||:||:.||||||||:.||
pombe     7 DLDSIIDRLLEVRGSRPGRQVQLSEDEIRFLCNKAREIFISQPILLELEAPLKICGDIHGQYYDL 71

  Fly    69 LRIFKACGFPPKANYLFLGDYVDRGKQSLETICLLFAYKVKYPLNFFLLRGNHESASINKIYGFY 133
            ||:|:..||||:||||||||||||||||||.||||.|||:|||.|||:||||||.||||:|||||
pombe    72 LRLFEYGGFPPEANYLFLGDYVDRGKQSLEVICLLLAYKIKYPENFFILRGNHECASINRIYGFY 136

  Fly   134 DEIKRRHTVRLWHSFTDCFNWLPVAALVGERIFCCHGGLSPSLRNLQQINHIQRPTDIPDEGIMC 198
            ||.|||:.::||.:||||||.||:||::.|:||..||||||.|.::.||..|.||||:||.|::|
pombe   137 DECKRRYNIKLWKTFTDCFNCLPIAAIIDEKIFTMHGGLSPDLNSMDQIQRIMRPTDVPDTGLLC 201

  Fly   199 DLLWADLNHTTKGWGHNDRGVSFTFDKVIVRDFLKAFDLQLMVRAHEVVEDGYEFFANRQLVTVF 263
            ||||:|.:....|||.|||||||||...:|..||...|:.|:.|||:|||||||||:.|||||:|
pombe   202 DLLWSDPDKDLTGWGDNDRGVSFTFGPDVVSRFLHKHDMDLVCRAHQVVEDGYEFFSKRQLVTLF 266

  Fly   264 SAPNYCGMMNNAGGVMSVSTDLICSFVIILPCHK 297
            |||||||..:|||.:|||...|:|||.|:.|..|
pombe   267 SAPNYCGEFDNAGAMMSVDESLLCSFQILKPAEK 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PpY-55A	NP_001286554.1	PTZ00480	8..310	CDD:185658	181/294 (62%)
PpY-55A	NP_001286554.1	MPP_PP1_PPKL	8..294	CDD:277359	179/289 (62%)
dis2	NP_596317.1	PTZ00480	5..311	CDD:185658	181/294 (62%)
dis2	NP_596317.1	MPP_PP1_PPKL	7..297	CDD:277359	179/289 (62%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53795
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11668
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.880