DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PpY-55A and Ppp1cb

DIOPT Version :9

Sequence 1:	NP_001286554.1	Gene:	PpY-55A / 48532	FlyBaseID:	FBgn0003140	Length:	314	Species:	Drosophila melanogaster
Sequence 2:	NP_766295.2	Gene:	Ppp1cb / 19046	MGIID:	104871	Length:	327	Species:	Mus musculus

Alignment Length:	293	Identity:	186/293 - (63%)
Similarity:	227/293 - (77%)	Gaps:	4/293 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 IDCIIKELTSLNGSE----CTLKEELIERLIQQTREVIKWQPMLLELQAPVNICGDIHGQFTDLL 69
            :|.:|..|..:.|..    ..:.|..:..|..::||:...||:||||:||:.||||||||:||||
Mouse     8 VDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLL 72

  Fly    70 RIFKACGFPPKANYLFLGDYVDRGKQSLETICLLFAYKVKYPLNFFLLRGNHESASINKIYGFYD 134
            |:|:..||||:|||||||||||||||||||||||.|||:|||.||||||||||.||||:||||||
Mouse    73 RLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYD 137

  Fly   135 EIKRRHTVRLWHSFTDCFNWLPVAALVGERIFCCHGGLSPSLRNLQQINHIQRPTDIPDEGIMCD 199
            |.|||..::||.:||||||.||:||:|.|:||||||||||.|::::||..|.||||:||.|::||
Mouse   138 ECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCD 202

  Fly   200 LLWADLNHTTKGWGHNDRGVSFTFDKVIVRDFLKAFDLQLMVRAHEVVEDGYEFFANRQLVTVFS 264
            |||:|.:...:|||.|||||||||...:|..||...||.|:.|||:||||||||||.|||||:||
Mouse   203 LLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFS 267

  Fly   265 APNYCGMMNNAGGVMSVSTDLICSFVIILPCHK 297
            ||||||..:||||:|||...|:|||.|:.|..|
Mouse   268 APNYCGEFDNAGGMMSVDETLMCSFQILKPSEK 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PpY-55A	NP_001286554.1	PTZ00480	8..310	CDD:185658	186/293 (63%)
PpY-55A	NP_001286554.1	MPP_PP1_PPKL	8..294	CDD:277359	184/288 (64%)
Ppp1cb	NP_766295.2	MPP_PP1_PPKL	7..297	CDD:277359	184/288 (64%)
Ppp1cb	NP_766295.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	305..327
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53795
OrthoDB	1	1.010	-	-		D327461at33208
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.830