DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pp1-13C and PPT1

DIOPT Version :9

Sequence 1:	NP_524921.1	Gene:	Pp1-13C / 48531	FlyBaseID:	FBgn0003132	Length:	302	Species:	Drosophila melanogaster
Sequence 2:	NP_011639.3	Gene:	PPT1 / 853023	SGDID:	S000003355	Length:	513	Species:	Saccharomyces cerevisiae

Alignment Length:	329	Identity:	108/329 - (32%)
Similarity:	165/329 - (50%)	Gaps:	50/329 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAEVLNLESI---------------ISRLLEVRGARPGKNVQLSEGE-----IRGLCLKSR---- 41
            :.:.|||.|.               ..:|.:.:.|..|..::....|     :..|.||.:
Yeast   147 LCQTLNLSSFDANADLANYEGPKLEFEQLYDDKNAFKGAKIKNMSQEFISKMVNDLFLKGKYLPK 211

  Fly    42 -----------EILLAQPILLELE------APLKICGDIHGQYYDLLRLF-EYGGYPPEANYLFL 88
                       .:...:|.::|||      ..:.:|||.|||:||:|.|| ::|...|:..|||.
Yeast   212 KYVAAIISHADTLFRQEPSMVELENNSTPDVKISVCGDTHGQFYDVLNLFRKFGKVGPKHTYLFN 276

  Fly    89 GDYVDRGKQSLETICLLLAYKIKYSENFFLLRGNHECASINRIYGFYDECKRRYTIKLWKTFTDC 153
            ||:||||..|.|...|....||.:..||||.|||||..::|:||||.||||.:|:.:::..|...
Yeast   277 GDFVDRGSWSCEVALLFYCLKILHPNNFFLNRGNHESDNMNKIYGFEDECKYKYSQRIFNMFAQS 341

  Fly   154 FNCLPVVAIVDEKIFCCHGGLSPD----LTSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDTIGW 214
            |..||:..:::......||||..|    |:..:.|.|..:|   |..|...:|||:|| ::..|.
Yeast   342 FESLPLATLINNDYLVMHGGLPSDPSATLSDFKNIDRFAQP---PRDGAFMELLWADP-QEANGM 402

  Fly   215 GENDRGVSFTFGAEVVVKFLQKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGA 279
            |.:.||:...||.::..:||:.:.|..|.|:|::...|.:|..|.:|:|:|||||||....|.|.
Yeast   403 GPSQRGLGHAFGPDITDRFLRNNKLRKIFRSHELRMGGVQFEQKGKLMTVFSAPNYCDSQGNLGG 467

  Fly   280 MMSV 283
            ::.|
Yeast   468 VIHV 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pp1-13C	NP_524921.1	PTZ00480	5..299	CDD:185658	108/325 (33%)
Pp1-13C	NP_524921.1	MPP_PP1_PPKL	6..296	CDD:277359	107/324 (33%)
PPT1	NP_011639.3	PLN03088	10..>130	CDD:215568
		TPR repeat	12..40	CDD:276809
		TPR repeat	45..75	CDD:276809
		TPR repeat	80..108	CDD:276809
		MPP_PP5_C	165..508	CDD:277362	104/311 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810