DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Pp1-13C and Ppp3ca

DIOPT Version :9

Sequence 1:NP_524921.1 Gene:Pp1-13C / 48531 FlyBaseID:FBgn0003132 Length:302 Species:Drosophila melanogaster
Sequence 2:NP_058737.1 Gene:Ppp3ca / 24674 RGDID:3382 Length:521 Species:Rattus norvegicus


Alignment Length:289 Identity:113/289 - (39%)
Similarity:170/289 - (58%) Gaps:25/289 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly    24 KNVQLSEGEIRGLCLKSREILLAQPILLELEAPLKICGDIHGQYYDLLRLFEYGGYPPEANYLFL 88
            |..:|.|.....:..:...||..:..||:::||:.:|||||||::||::|||.||.|....||||
  Rat    52 KEGRLEESVALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFL 116

  Fly    89 GDYVDRGKQSLETICLLLAYKIKYSENFFLLRGNHECASINRIYGFYDECKRRYTIKLWKTFTDC 153
            |||||||..|:|.:..|.|.||.|.:..|||||||||..:...:.|..|||.:|:.:::....|.
  Rat   117 GDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMDA 181

  Fly   154 FNCLPVVAIVDEKIFCCHGGLSPDLTSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDTIGWGEND 218
            |:|||:.|:::::..|.||||||::.:::.||::.|..:.|..|.:||:|||||.:|   :|...
  Rat   182 FDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLED---FGNEK 243

  Fly   219 ----------RGVSFTFGAEVVVKFLQKHDLDLICRAHQVVEDGYEFFAKRQ------LVTLFSA 267
                      ||.|:.:....|..|||.::|..|.|||:..:.||..:.|.|      |:|:|||
  Rat   244 TQEHFTHNTVRGCSYFYSYPAVCDFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSA 308

  Fly   268 PNYCGEFDNAGAMMSVDNTLM------CS 290
            |||...::|..|::..:|.:|      ||
  Rat   309 PNYLDVYNNKAAVLKYENNVMNIRQFNCS 337

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Pp1-13CNP_524921.1 PTZ00480 5..299 CDD:185658 113/289 (39%)
MPP_PP1_PPKL 6..296 CDD:277359 113/289 (39%)
Ppp3caNP_058737.1 MPP_PP2B 41..345 CDD:277361 113/289 (39%)
Catalytic. /evidence=ECO:0000305 56..340 112/285 (39%)
SAPNY motif. /evidence=ECO:0000250|UniProtKB:Q08209 307..311 3/3 (100%)
Interaction with PxIxIF motif in substrate. /evidence=ECO:0000250|UniProtKB:Q08209 327..336 1/8 (13%)
Calcineurin B binding. /evidence=ECO:0000250|UniProtKB:Q08209 341..369
Calmodulin-binding. /evidence=ECO:0000250|UniProtKB:Q08209 392..406
Autoinhibitory segment. /evidence=ECO:0000250|UniProtKB:P16298 407..414
Autoinhibitory domain. /evidence=ECO:0000269|PubMed:1322410 465..487
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 475..521
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0639
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG53795
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
43.820

Return to query results.
Submit another query.