DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pp1-13C and Ppef2

DIOPT Version :9

Sequence 1:	NP_524921.1	Gene:	Pp1-13C / 48531	FlyBaseID:	FBgn0003132	Length:	302	Species:	Drosophila melanogaster
Sequence 2:	XP_030110066.1	Gene:	Ppef2 / 19023	MGIID:	1342304	Length:	797	Species:	Mus musculus

Alignment Length:	397	Identity:	101/397 - (25%)
Similarity:	151/397 - (38%)	Gaps:	139/397 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 QLSEGEIRGLCLKSREILLAQPILLELEA----PLKICGDIHGQYYDLLRLFEYGGYP-PEANYL 86
            ||....:..|..::|:.|...|.:..:..    .:.:|||:|||..||:.:|...|.| ||..|:
Mouse   180 QLHARYVLNLLYETRKHLAQLPNINRVSTCYSEEVTVCGDLHGQLDDLIFIFYKNGLPSPERAYV 244

  Fly    87 FLGDYVDRGKQSLETICLLLAYKIKYSENFFLLRGNHECASINRIYGFYDECKRRYTI---KLWK 148
            |.||:|||||.|:|.:.:|.|:.:.|.:.|.|.|||||...:|..|||..|...:|.|   |:.:
Mouse   245 FNGDFVDRGKDSVEVLMVLFAFMLVYPKEFHLNRGNHEDHLVNLRYGFTKEVMHKYKIHGKKILR 309

  Fly   149 TFTDCFNCLPVVAIVDEKIFCCHGGLSPDLTSME------------------------------- 182
            |..|.|..||:..:||||:...|||:| |.|.:|
Mouse   310 TLQDVFCWLPLATLVDEKVLVLHGGVS-DKTDLELLAKLDRHKIVSTMRCKTRKESENREEQKRK 373

  Fly   183 ---------------------------------------------------------QIRR---- 186
                                                                     |:||
Mouse   374 DNQTSSGQKPTPWFLPQSRSLPSSPFHLGSGFKAYKAGRSCSIPCGSPNSKELSRRGQVRRSVDL 438

  Fly   187 -----------------------------------IMRPTDVPDQ-GLLCDLLWSDPDKDTIGWG 215
                                               ::.||  |:: ..:.|:|||||........
Mouse   439 ELEQCRQQAGFLGIREKGESLPLAPDADCVADGGGVLEPT--PEEWKQVVDILWSDPAAQEGCKA 501

  Fly   216 ENDRGVSFTFGAEVVVKFLQKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAM 280
            ...||....||.:|..:.::|:.|.|:.|:|:...:||||...|:::|:|||.||.....|.||.
Mouse   502 NAVRGGGCYFGPDVTERLMEKYKLQLLIRSHECKPEGYEFCHNRKVLTIFSASNYYEVGSNRGAY 566

  Fly   281 MSVDNTL 287
            :.:...|
Mouse   567 VKLGPAL 573

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pp1-13C	NP_524921.1	PTZ00480	5..299	CDD:185658	101/397 (25%)
Pp1-13C	NP_524921.1	MPP_PP1_PPKL	6..296	CDD:277359	101/397 (25%)
Ppef2	XP_030110066.1	IQ	61..80	CDD:197470
		MPP_RdgC	162..581	CDD:277364	101/397 (25%)
		FRQ1	621..765	CDD:227455
		EFh	701..766	CDD:238008
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.900