Protein Alignment CNOT3 and cnot3

DIOPT Version :10

• Sequence 1: NP_001427582.1
• Gene: CNOT3 / 4849
• HGNCID: 7879
• Length: 771
• Species: Homo sapiens
• Sequence 2: NP_001121452.1
• Gene: cnot3 / 100158546
• XenbaseID: XB-GENE-6087000
• Length: 727
• Species: Xenopus tropicalis
• Alignment Length: 779
• Identity: 600/779 - (77%)
• Similarity: 649/779 - (83%)
• Gaps: 60/779 - (7%)

Human     1 MADKRKLQGEIDRCLKKVSEGVEQFEDIWQKLHNAANANQKEKYEADLKKEIKKLQRLRDQIKTW 65
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 Frog     1 MADKRKLQGEIDRCLKKVSEGVEQFEDIWQKLHNAANANQKEKYEADLKKEIKKLQRLRDQIKTW 65

Human    66 VASNEIKDKRQLIDNRKLIETQMERFKVVERETKTKAYSKEGLGLAQKVDPAQKEKEEVGQWLTN 130
            |||||||||||||:|||||||||||||||||||||||||||||||||||||||||||:|||||||
 Frog    66 VASNEIKDKRQLIENRKLIETQMERFKVVERETKTKAYSKEGLGLAQKVDPAQKEKEDVGQWLTN 130

Human   131 TIDTLNMQVDQFESEVESLSVQTRKKKGDKDQKQDRIEGLKRHIEKHRYHVRMLETILRMLDNDS 195
            |||||||.||||||||||||||||||||||||||||||||||||||||||:||||||||||||||
 Frog   131 TIDTLNMGVDQFESEVESLSVQTRKKKGDKDQKQDRIEGLKRHIEKHRYHIRMLETILRMLDNDS 195

Human   196 ILVDAIRKIKDDVEYYVDSSQDPDFEENEFLYDDLDLEDIPQALVATSPPSHSHMEDEIFNQSSS 260
            |.|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 Frog   196 INVDAIRKIKDDVEYYVDSSQDPDFEENEFLYDDLDLEDIPQALVATSPPSHSHMEDEIFNQSSS 260

Human   261 TPTSTTSSSPIPPSPANCTT---ENSEDDKK-RGRSTDSEVSQSPAKNGSKPVHSNQHPQSPAVP 321
            ||||||||||||||||.|||   |||||||| |||||||||||||||||||.||:|.|||||||.
 Frog   261 TPTSTTSSSPIPPSPATCTTVSAENSEDDKKIRGRSTDSEVSQSPAKNGSKSVHNNHHPQSPAVT 325

Human   322 PTYPSGP-PPAASALSTTPG---NNGVPAPAAPPSALGPKASPAPSHNSGTPAPYAQAVAPPAPS 382
            |:|..|. ...:|:|...||   |..|...::..|:...|.:||..|.||||.|||||||||: |
 Frog   326 PSYQIGSNSSTSSSLGNGPGTNSNGAVSNSSSTNSSSNSKNNPASGHTSGTPTPYAQAVAPPS-S 389

Human   383 GPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGGAGKQNGATSYSSVVADSPAEVALSSSG 447
            ..:|:||||||.|                 .|:|      |||||:|||||||::..:.:||:|.
 Frog   390 NTNTSQPRPPSAQ-----------------QNTS------KQNGASSYSSVVAENSTDSSLSNSS 431

Human   448 GNNASSQALGPPSGPHNPPPSTSKEPSAAAPTGAGGVAPGSGNNSGGPSLLVPLPVNPPSSPTPS 512
            ...:|...:      ||||.|::|...:::...|     .:.:.|.|.|||:||.|||||||||:
 Frog   432 QTQSSQSVI------HNPPTSSAKSDISSSSQPA-----NNSSTSTGSSLLLPLNVNPPSSPTPN 485

Human   513 FSDAKAAGALLNGPPQFSTAPEIKAPEPLSSLKSMAERAAISSGIEDPVPTLHLTERDIILSSTS 577
            |||.|.:..||||||||::..|||||||||:||||||||||.|.:||||||:||.||::::::|:
 Frog   486 FSDPKPSQPLLNGPPQFASTAEIKAPEPLSTLKSMAERAAIGSSLEDPVPTIHLAEREMLITTTT 550

Human   578 APPASAQPPLQLSEVNIPLSLGVCPLGPVPLTKEQLYQQAMEEAAWHHMPHPSDSERIRQYLPRN 642
            |.|.|:|||.||||||||||||||||||||||.:||||||||:||||||||||||||||||||||
 Frog   551 AQPPSSQPPTQLSEVNIPLSLGVCPLGPVPLTTDQLYQQAMEDAAWHHMPHPSDSERIRQYLPRN 615

Human   643 PCPTPPYHHQMPPPHSDTVEFYQRLSTETLFFIFYYLEGTKAQYLAAKALKKQSWRFHTKYMMWF 707
            ||||||||||:||||||||||||||||||||||||||||||||||||||||||||||||||||||
 Frog   616 PCPTPPYHHQIPPPHSDTVEFYQRLSTETLFFIFYYLEGTKAQYLAAKALKKQSWRFHTKYMMWF 680

Human   708 QRHEEPKTITDEFEQIPDHLLVHSLTAFSPGQGTYIYFDYEKWGQRKKEGFTFEYRYLEDRDLQ 771
            ||||||||||||||                 |||||||||||||||||||||||||||||||||
 Frog   681 QRHEEPKTITDEFE-----------------QGTYIYFDYEKWGQRKKEGFTFEYRYLEDRDLQ 727

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CNOT3	NP_001427582.1	None
cnot3	NP_001121452.1	Not3	3..230	CDD:461155	221/226 (98%)
		PHA03247	<479..629	CDD:223021	118/149 (79%)
		NOT2_3_5	594..719	CDD:461199	123/141 (87%)