Protein Alignment Grip91 and tubgcp3

DIOPT Version :9

• Sequence 1: NP_524919.2
• Gene: Grip91 / 48481
• FlyBaseID: FBgn0001612
• Length: 917
• Species: Drosophila melanogaster
• Sequence 2: XP_005171052.1
• Gene: tubgcp3 / 563517
• ZFINID: ZDB-GENE-030616-538
• Length: 906
• Species: Danio rerio
• Alignment Length: 956
• Identity: 306/956 - (32%)
• Similarity: 491/956 - (51%)
• Gaps: 115/956 - (12%)

  Fly    11 VATNSTDISNIINEMIIC-IKGKQMPEV-HEKAMDHLSKMIAAN--SRVIRDSNMLTERECVQKI 71
            :||......|::.:.:.| |.||...:| |:  ..:..::|.:|  ..:.||..:::|     ||
Zfish     1 MATLDQKSPNVLLQSLCCKITGKSEADVAHQ--FQYAVRVIGSNYAPTIERDEFLVSE-----KI 58

  Fly    72 MKLLSARNKKEEGKTVSDHFNELYRKLTLTKCDPHMRHSLMTHLLTMTDNSDAEKAVASEDPRTQ 136
            .|.|..:.::.:...    |:||:|||.......| |.|::..||::           .||||..
Zfish    59 KKELLKQRREADAAL----FSELHRKLQTQGVLKH-RWSILYLLLSL-----------CEDPRKP 107

  Fly   137 CDNL-------------------TQILVSRLNSI------------SSSIAS--LNEMGVVNGNG 168
            ...:                   |....:|..|:            :||:|:  ::.|||.:.||
Zfish   108 SGRVPVCSYGALLAQALPRDVHSTPFYYARPQSLPLSYPERSATAHNSSMATSGISSMGVFSING 172

  Fly   169 VGAAAVTGAAAVTGAAAVTGAAAVTGAAASHSYDATQSSIGL----RKQSLPNYLDATKMLPESR 229
            .|.   |..:.:|||.......::.|:..:.:...:.|..|.    |..|.|:...|.|.|...|
Zfish   173 PGP---TPPSLLTGAGTQAVGESMRGSRLAWTLPVSSSPSGAAAAPRPPSGPSSSPAPKPLQRPR 234

  Fly   230 HD-----------IVMSAIYSFTGVQGKYLKKDVVTGRFKLDQQ--NIKFLTTGQAGMLLRLSEL 281
            .|           :|...:|.|.|:.||::|.......:|:|.:  ..|.|....:    ||:||
Zfish   235 RDGDGSADIGEAALVRDILYVFQGIDGKFIKMCSPENCYKIDSKVPLCKSLRDTSS----RLAEL 295

  Fly   282 GYYHDRVVKFSDVSTGFNAIGSMGQALISKLKEELANFHGQVAMLHDEMQRFRQASVNGIANKGK 346
            |:.|:::.|::|..:...|.|.:||:..:.|.:||..::..:::||.::|......||
Zfish   296 GWLHNKIRKYTDSHSLDRAFGLVGQSFCAALHQELKEYYRLLSVLHAQLQVEDDQGVN------- 353

  Fly   347 KDSGPDAGDEMTLFKLLAWYIKPLHRMQWLTKIADACQVKKGGDLASTVYDFLDNGNDMVNKLVE 411
                ......:||.:||.|...|..|::.|..:.|.||.:|||:||:.|:.:...|:..:..|::
Zfish   354 ----MSVDSSLTLRRLLVWTYDPKVRLKTLAALVDYCQGRKGGELATAVHAYGKTGDPNMRALIQ 414

  Fly   412 DLLTAICGPLVRMISKWILEGGISDMHREFFVKSIKDVGVDRLWHDKFRLRLPMLPKFVPMDMAN 476
            .:|..:..|::..:.:||.:|.:.|.:.||||.|...|..|||||||:.||..|:|.|:.||.|.
Zfish   415 HILGLVSHPILNFLYRWIYDGELEDTYHEFFVASDPTVKTDRLWHDKYSLRKSMIPSFITMDQAR 479

  Fly   477 KILMTGKSINFLREICEEQGMMKERDELMKVMESS--------ASQIFSYTPDTSWHAAVETCYQ 533
            |:|:.|||||||.::|.      :|....|:|.:|        |:::|:....| :.:.::..|.
Zfish   480 KVLLIGKSINFLHQVCH------DRTPPGKIMPASKSKDSPKDAAELFTDLEGT-FQSKIDAAYF 537

  Fly   534 QTSKHVLDIMVGPHKLLDHLHGMRRYLLLGQGDFISILIENMKNELERPGLDIYANDLTSMLDSA 598
            :|||::||::...::||:||..|||||||||||||..|::.:|.||.||...:|.::||.:|::|
Zfish   538 ETSKYLLDVLNKNYQLLEHLQAMRRYLLLGQGDFIRHLMDLLKPELARPATTLYQHNLTGILETA 602

  Fly   599 LRCTNAQYDDPDILNHLDVIVQRPFNGDIGWNIISLQYIVHGPLAAML-ESTMPTYKVLFKPLWR 662
            :|.||||:|.|:||..|||.:.....||.||::.||.|.|.||:|.:. ...|..|..:|..|||
Zfish   603 VRATNAQFDSPEILKRLDVRLLEVSPGDTGWDVFSLDYHVEGPIATVFTRECMSHYLRVFNFLWR 667

  Fly   663 MKHMEFVLSMKIWKEQMGNAKALRTMKSEIGKASHRLNLFTSEIMHFIHQMQYYVLFEVIECNWV 727
            .|.||::|: .|||.||.|||.|::| .|:....|:.::..||::|||||||||:.|||:||:|.
Zfish   668 AKRMEYILT-DIWKGQMCNAKLLKSM-PELSGVLHQCHVLASEMVHFIHQMQYYITFEVLECSWD 730

  Fly   728 ELQKKMQKATTLDEILEAHEKFLQTILVGCFVS-NKASVEHSLEVVYENIIELEKWQSSFYKDCF 791
            ||..|:|:|..||.|:.||:.||.||:..|.:. |..|:.:.|..|::.|||.:..|.:.|:...
Zfish   731 ELWNKVQQAQDLDHIIAAHDVFLDTIISRCLLDVNNRSLLNQLRAVFDQIIEFQNAQDTLYRSAL 795

  Fly   792 KELNARKELSKIVEKSEKKGVYGLTNKMILQRDQEAKIFAEKMDIACRGLEVIATDYEKAVSTFL 856
            :||..|.:......:.|:...:|:|.:...:.::..:.|.:.:...|..|.::...|:..|..||
Zfish   796 EELQLRIQFEDKKRQREEMAEWGVTAEQEAEENRRVQEFKDTIPKMCSQLRLLTHFYQGIVQEFL 860

  Fly   857 MSLNSSDDPNLQLFGTRLDFNEYYKKRDTNLSKPL-TFEHMRMSNV 901
            ..|.:..|.:||....||||||:||.||..|...| .....|.||:
Zfish   861 RLLMTCSDESLQFLSFRLDFNEHYKARDPRLRPSLGATRGRRSSNI 906

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grip91	NP_524919.2	Spc97_Spc98	236..758	CDD:282045	203/532 (38%)
tubgcp3	XP_005171052.1	Spc97_Spc98	251..761	CDD:282045	203/533 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583589
Domainoid	1	1.000	261	1.000	Domainoid score	I1922
eggNOG	1	0.900	-	-		E1_KOG2000
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4609
Inparanoid	1	1.050	450	1.000	Inparanoid score	I1587
OMA	1	1.010	-	-		QHG55181
OrthoDB	1	1.010	-	-		D124154at33208
OrthoFinder	1	1.000	-	-		FOG0004051
OrthoInspector	1	1.000	-	-		oto40650
orthoMCL	1	0.900	-	-		OOG6_101925
Panther	1	1.100	-	-	LDO	PTHR19302
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R54
SonicParanoid	1	1.000	-	-		X3891
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	17	16.800