Protein Alignment Grip91 and tubgcp4

DIOPT Version :10

• Sequence 1: NP_524919.2
• Gene: Grip91 / 48481
• FlyBaseID: FBgn0001612
• Length: 917
• Species: Drosophila melanogaster
• Sequence 2: NP_001128602.1
• Gene: tubgcp4 / 557155
• ZFINID: ZDB-GENE-081022-124
• Length: 668
• Species: Danio rerio
• Alignment Length: 720
• Identity: 144/720 - (20%)
• Similarity: 271/720 - (37%)
• Gaps: 193/720 - (26%)

  Fly   262 QNIKFLTTGQAGMLLRLSELGYYHDRVVKFSDVSTGF-------------------------NAI 301
            |::.||...:..:|.||.::|..:.|..:|.:..||.                         ..:
Zfish    29 QDLPFLHPSETSVLNRLCKMGTDYVRFTEFIEQHTGHVHQQEHYSSQPSQSGLHGIYLRAFCTGL 93

  Fly   302 GSM----GQALISKLKEELANFHGQVAMLHDEMQRFRQASVNGIANKGKKDSGPDAGDEMTLFKL 362
            .||    .|||:...||.|.:.|..::.::..:::|:                       .||..
Zfish    94 HSMLQPYRQALLDLEKEFLGDPHLSISHVNYMLEQFQ-----------------------LLFPS 135

  Fly   363 LAWYIKPLHRMQWLTKIADACQVKKGGDLASTVYDFLDNGNDMVNKLVEDLLTAICGPLVRMISK 427
            :...::.:...:     ...||:      ..|||.....|...|...:|.:|....|.:.:.::.
Zfish   136 VMVVVETIKSQK-----IHGCQI------LETVYKHSCGGLPPVRMALEKILAVCHGVMYKQLAA 189

  Fly   428 WILEGGISDMHREFFVK--------------SIKDVGVD-------------RLWHD-------- 457
            |:|.|.:.|...|||||              ..:|:|:.             ||..:
Zfish   190 WMLHGLLLDQSEEFFVKQGPSAGGATAAQEEDEEDLGIGGLSGKQLRELQDLRLIEEENMLAPSL 254

  Fly   458 -KFRLRLPMLPKFVPMDMANKILMTGKSI----NFLREICEEQGMMKERDELM--KVMESSASQI 515
             :|.||:.|||.::|:.:|.|||..|:|:    |..:.......::|.::::.  ::.......:
Zfish   255 QQFSLRVEMLPSYIPVRVAEKILFVGESVQMFENHNQSPSRAGSILKHQEDMFAAELHRLKQQPL 319

  Fly   516 FSYTPDTSWHAAVETCYQQTSKHVLDIMVGPHKLLDHLHGMRRYLLLGQGDFISILIENMKNELE 580
            ||.   ..:...|:......::|:..:||....||..|..::.:.|||:|:...:.|:..::.|:
Zfish   320 FSL---VDFENLVDGIRSTVAEHLWTLMVEESDLLGQLKIIKDFFLLGRGELYQVFIDLAQHMLK 381

  Fly   581 RPGLDIYANDLTSMLDSALRCTNAQYDDPDILNHLDVIVQRPFNG-------------------- 625
            .|...:..:|:......|..  ....||.::|..|.:.:.  ::|
Zfish   382 TPPSAVTEHDVNVAFQQAAH--KVLLDDDNLLPLLHLTID--YHGKESKEGSGNREGTTPPQESS 442

  Fly   626 -----DIGWNIISLQYIVHGPL-----AAMLESTMPTYKVLFKPLWRMKHMEFVLSMKIWKEQMG 680
                 ..||..:.|.|.|..||     .|:||.    |.|:|:.|..::.::..| ...|..||
Zfish   443 PREAPPTGWAALGLAYKVQWPLHILFTPAVLEK----YNVVFRYLLSVRRVQSEL-QHCWALQM- 501

  Fly   681 NAKALRTMKSEIGKASHRLNLFTSEIMHFIHQMQYYVLFEVIECNWVELQKKMQKATTLDEILEA 745
            ..|.|::.:::..|...|     :.:...:..:|||:..:|:|..:.:|.:::......:.|..|
Zfish   502 QRKHLKSNQTDAVKWRLR-----NHMAFLVDNLQYYLQVDVLESQFSQLLQQINSTRDFESIRLA 561

  Fly   746 HEKFLQTILVGCFVSNKASVEHSLEVVYENIIELEKWQSSFYKDCFKELNARKELSKIVEKSEKK 810
            |:.||..:|...|:..| .|.|.|    ..|::|          |.   |....:|:.:...:::
Zfish   562 HDHFLSNLLAQSFILLK-PVFHCL----NEILDL----------CH---NFCSLVSQNLGSLDER 608

  Fly   811 GVYGLTNKMILQRDQEAKIFAEKMDIACRGLEVIATDYEKAVSTFLMSLNSSDDPNLQLFGTRLD 875
            |                   ..::||..:|....:....|.:|:......:||...|.|   |||
Zfish   609 G-------------------TAQLDILVKGFSRQSFLLFKILSSVRNHQINSDLAQLLL---RLD 651

  Fly   876 FNEYY 880
            :|:||
Zfish   652 YNKYY 656

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grip91	NP_524919.2	GCP_N_terminal	230..544	CDD:465456	65/352 (18%)
		GCP_C_terminal	549..880	CDD:461187	75/360 (21%)
tubgcp4	NP_001128602.1	GCP_N_terminal	2..347	CDD:465456	67/354 (19%)
		GCP_C_terminal	350..656	CDD:461187	75/360 (21%)