Protein Alignment Grip91 and Grip75

DIOPT Version :10

• Sequence 1: NP_524919.2
• Gene: Grip91 / 48481
• FlyBaseID: FBgn0001612
• Length: 917
• Species: Drosophila melanogaster
• Sequence 2: NP_609412.1
• Gene: Grip75 / 34441
• FlyBaseID: FBgn0026431
• Length: 650
• Species: Drosophila melanogaster
• Alignment Length: 670
• Identity: 125/670 - (18%)
• Similarity: 246/670 - (36%)
• Gaps: 183/670 - (27%)

  Fly   322 QVAMLHDEMQRFRQASVNGIANKGKKDSG----PDA-----------GDEMTLFKLLAWYIKPLH 371
            ::..::.|:::|..:|       |:|...    ||:           |.||.|.:    |...:.
  Fly    45 KIIKVYQEVEQFTHSS-------GRKSDTHGELPDSLHGYYLLNLAKGIEMALEE----YYAEIG 98

  Fly   372 RMQ---------WLTKIADACQVK-------------------KGGDLASTVYDFLDNGNDMVNK 408
            |::         .|:.:.:|...|                   :|..|...::...::|:..:.|
  Fly    99 RLEKYCLGNERNSLSYVYNALYAKFPLLVFMRNLITEIHVLNLRGCVLLHNLHQQCEHGDIQLEK 163

  Fly   409 LVEDLLTAICGPLVRMISKWILEGGISDMHREFFVK---------------------SIKDVGVD 452
            .::.::..:.......::.|:|.|.|.|:|.|||:|                     |.:....|
  Fly   164 AIKIIMKPVKNAFFSSLAHWLLFGVIDDVHSEFFIKFTPTDAVDGSSFSKSATCSLLSAEKNPED 228

  Fly   453 RLWHDKFRLRLPMLPKFVPMDMANKILMTGKSINFLR----------------EICEEQGMMKER 501
            .:|  ::.:.:..||.|..:.:|.|:|..|:::...:                ::.|     .:.
  Fly   229 YIW--QYEVNMSQLPGFFSIVLAEKVLFVGQTVLVFKMGRNVKVKNKTDPLAAKLAE-----LDS 286

  Fly   502 DELMKVMESSASQIFSYTPDTSWHAAVET---------CYQQTSKHVLDIMVGPHKLLDHLHGMR 557
            |::.::.....|:.|....|.|....:..         .....|..:.:|.|....|...:..::
  Fly   287 DDIYQLWSGRESEFFKMVVDLSNEDTINVFRLEKVIIDIKNYVSARLSEIAVNEVDLERQMGLIK 351

  Fly   558 RYLLLGQGDFISILIENMKNELERPGLDIYANDLTSMLDSALRCTNAQYDDPDILNHLDVIVQR- 621
            .:.|||:|:|.......|...:|....:.:.| :|...:.|...|..    .|.|:...:|.||
  Fly   352 DFFLLGRGEFYLEFCSQMVGTMETYREERFKN-VTRSFELAATVTGI----TDDLDKFSLICQRS 411

  Fly   622 --------PFNGDIGWNIISLQYIVHGPLAAMLE-STMPTYKVLFKPLWRMKHMEFVLSMKIWKE 677
                    .||...|   :||:|....||..:.. :|:..|..:|:.|..::..::.: .::|.:
  Fly   412 TSEPDDTSDFNFLQG---LSLKYEYEWPLNLLFSPTTIERYNNIFRFLLIIRTYQYEI-QRVWAK 472

  Fly   678 QMGNAKALRTMKSEIGKASHRLNLFTSEIMHFIHQMQYYVLFEVIECNWVELQKKMQKATTLDEI 742
            |...||:.:.:     ..::::....:.:|.|::.||||:..:|:|..:..|...::..:..:.|
  Fly   473 QTWRAKSAKDV-----PPNNKIITLRNYLMFFLNNMQYYIQVDVLESQFGILMNVIKSRSDFEVI 532

  Fly   743 LEAHEKFLQTILVGCFVSNKASVEHSLEV--------VYENIIEL----EKWQSSFYKDCFKELN 795
            ..||..||..:|..||:.|::  |..|.|        :|..:::|    ||         |..:.
  Fly   533 QRAHTVFLANVLSHCFLLNES--ETQLNVTGSQNRNPIYGTLLKLFGICEK---------FAHMT 586

  Fly   796 ARKELSKIVEKSEKKGVYGLTNKMILQRDQEAKIFAEKMDIACRGLEVIATDYEKAVSTFLMSLN 860
            ..|:.|..:|                   .|.....|...:....|..:..|.:.|
  Fly   587 QTKDPSDDLE-------------------DEVDQLNESFGVQIASLIQLLVDVKSA--------- 623

  Fly   861 SSDDPNLQLFGTRLDFNEYY 880
            |...|..||. .|||||.::
  Fly   624 SCLGPLSQLL-LRLDFNCWF 642

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grip91	NP_524919.2	GCP_N_terminal	230..544	CDD:465456	48/310 (15%)
		GCP_C_terminal	549..880	CDD:461187	76/352 (22%)
Grip75	NP_609412.1	GCP_N_terminal	2..340	CDD:465456	49/312 (16%)
		GCP_C_terminal	349..642	CDD:461187	75/346 (22%)