Protein Alignment Grip91 and Tubgcp6

DIOPT Version :9

• Sequence 1: NP_524919.2
• Gene: Grip91 / 48481
• FlyBaseID: FBgn0001612
• Length: 917
• Species: Drosophila melanogaster
• Sequence 2: NP_001156791.1
• Gene: Tubgcp6 / 328580
• MGIID: 2146071
• Length: 1769
• Species: Mus musculus
• Alignment Length: 1121
• Identity: 198/1121 - (17%)
• Similarity: 366/1121 - (32%)
• Gaps: 378/1121 - (33%)

  Fly    36 EVHEKA----MDHLSKMIAANSRVIRDSN-----------------MLTERECVQKIMKLLSARN 79
            |:..||    :||.||:.|..:|  |:..                 :|.:::|:|::::.:.|:.
Mouse   750 ELERKARQALVDHYSKLSAEAAR--REQKALWRIQRHRLESARLRFLLEDQKCIQEMLRDMEAQQ 812

  Fly    80 KKE---------------------EGKTVSDHFNELYRKLTLTKC--DPHMRHSL---------- 111
            .:|                     ||.:....|.||:.......|  .|.:..|.
Mouse   813 PQEPPSVFPSTGSQVTSTGPEHAGEGHSCDPGFTELHWGCPSLPCASTPSVPKSATEGADDSGAG 877

  Fly   112 -MTHLLTMTD----NSDAEKAVASEDP-------RTQCDNL------------------------ 140
             .:..|::||    :|..|:.|.:...       :|.|.:|
Mouse   878 PFSTGLSITDFLPVDSGEEQPVENTGVPFLEVALQTICSDLSPVAPEPAALTAGGPQATQSEYDF 942

  Fly   141 ---------TQILVSRLNSISSSIAS-----LNEMGVVNGNGVGAAAVTGAA--AVTGAAAVTGA 189
                     |.:.......:.:|:.|     |.:|.....:.:.....|...  .::.|..|.|:
Mouse   943 NTILRPAMATSLSPGPFQDVQNSVDSDKQHLLGDMSTKVDSYIHDMQETLPCPHPLSHATPVEGS 1007

  Fly   190 AAVTGAAASHSYDATQSSIGLRKQSLPNYLDATKMLPESRHDIVMSAIYSFTGVQ-GKYLKKDVV 253
            ....|....|..:.|.|:     :|..:.:...:.|..|||       .|...:: |.|: .||.
Mouse  1008 LQPVGQLLEHMSETTVST-----ESHASGMAPCQQLSISRH-------VSDANIKVGDYM-SDVA 1059

  Fly   254 TGRFKLDQQNIK-FLTTGQAGMLLRLSEL----------GYYHDRVVK----FSDVS---TGFNA 300
            ..|   .:.|:. .::....|:...::|:          |:..|..:|    .|||:   |.:|.
Mouse  1060 LPR---PRWNVHGHVSEASIGVGENMAEVAPSRPRWNVHGHVSDASIKIGENMSDVAPSRTRWNI 1121

  Fly   301 IGSMGQALISKLKEELA---------NFHGQVA--------MLHDEMQRFRQASVNGIANKGKKD 348
            .|.:..|.| |:.|.::         |.||.|:        .:.|......:.:|:|..::....
Mouse  1122 HGHVSDASI-KVGENVSDVTPSRPRWNVHGHVSEASIKVGENVSDVTPSRPRWNVHGHVSEASIK 1185

  Fly   349 SGPDAGDEMTLFKLLAWYIKPLHRMQWLT--KIADACQVKKGGDLASTVYDFLDNGNDMVNKLVE 411
            .|.:..|           :.| .|.:|..  .::|| .::.|.:::.|..|....|......::|
Mouse  1186 VGENVSD-----------VTP-SRPRWNVHGHVSDA-SIRIGENVSDTDLDLQQRGCAQPPLILE 1237

  Fly   412 DLLTAI-----------------------------CGPLVRMISKWIL--------EGGI----- 434
            :.|...                             |||.:...:|..:        ||.:
Mouse  1238 EPLPEAEADLKPHQCPPAHVSEAVLGVEAQSPALECGPQLPEKTKPTVCSGFGRTEEGSLQTKTL 1302

  Fly   435 --------SDMHREFFVKSIKDVGVDRLWHDKFRLRLPMLPKFVPMDMA--------NKILMT-- 481
                    |.:..|      |..|..|...|    ..|.||.....|.|        :::..|
Mouse  1303 VAEPSMLGSGIPEE------KGPGKSRDAED----LSPCLPSSSQEDTAVPSSPGPSDEVSNTEA 1357

  Fly   482 -----GKSINFLREICEEQGMMKERDELMKVMESSASQI--------FSYTPDTSWHAAVETCYQ 533
                 ||...:|.::.:...:.:..|....:.|...:.:        |::..|....:||:....
Mouse  1358 EARRWGKEQAYLTDLTKLYHLEQYPDSYDSMSEPPVAHLVHHMLPRAFAFPVDPQVQSAVDESAV 1422

  Fly   534 Q-------------------------TSKHVLDIMVGPHKLLDHLHGMRRYLLLGQGDFISILIE 573
            |                         .||..:|.......|..|...:|.:||:..|:|...|.:
Mouse  1423 QLSELLTLPVLMKRSLMAPLAAHVSLVSKAAVDYFFVELHLETHFEALRHFLLMEDGEFAQSLSD 1487

  Fly   574 NMKNEL---ERPGLDIYANDLTSMLDSALR---------CTNAQY-----------DDPDILNHL 615
            .:..:|   :.||..:....|.|:|..||:         .:|..:           :.||:|:.|
Mouse  1488 LLFEKLGAGQTPGELLNPLVLNSILSKALQYSLHGDTPHASNLSFALKYLPEVFAPNAPDVLSCL 1552

  Fly   616 DVIVQRPFNGDIGWNIISLQYIVHGPLAAML-ESTMPTYKVLFKPLWRMKHMEFVLSMKIWKEQM 679
            :                 |:|.|..||..:: ||.:..|..:|..|.::|.|.:.|     |:..
Mouse  1553 E-----------------LRYKVDWPLNIVITESCLNKYSGIFSFLLQLKLMMWTL-----KDIC 1595

  Fly   680 GNAKALRTMKSEIGKASHR-LNLFTSEIMHFIHQMQYYVLFEVIECNWVELQKKMQKATTLDEIL 743
            .:.|....:....|....| |.||..|:.||:..:|.|:..:::..:|.|.:.::.....|:||.
Mouse  1596 FHLKRTALVSHTAGSVQFRQLQLFKHEMQHFVKVIQGYIANQILHVSWCEFRARLAVVGDLEEIQ 1660

  Fly   744 EAHEKFL-QTILVGCFVSNKASVEHSLEVVYENIIELEKWQSSFYKDCFKELNARKELSKIVEKS 807
            .||.::| :.:..|......|.|.:.:..::..:::..                    |:::.::
Mouse  1661 RAHAEYLHRAVFRGLLTEKAAPVMNIIHSIFSLVLKFR--------------------SQLISQN 1705

  Fly   808 --EKKGVYGLTNKMILQRDQEAKIFAEKMDIACRGLEVIATDYEKAVSTFLMS-----LNSSDDP 865
              ...|..|..:.......|....|                   |..|.||..     :|....|
Mouse  1706 WGPATGPRGAEHPNFPLMQQSYSTF-------------------KYYSHFLFKVVTKLVNRGYQP 1751

  Fly   866 NLQLFGTRLDFNEYYK 881
            :|:.|..|::||.||:
Mouse  1752 HLEDFLLRINFNNYYQ 1767

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grip91	NP_524919.2	Spc97_Spc98	236..758	CDD:282045	128/683 (19%)
Tubgcp6	NP_001156791.1	Spc97_Spc98	355..>611	CDD:282045
		NBP1	<622..>752	CDD:285709	1/1 (100%)
		ARGLU	631..759	CDD:291991	3/8 (38%)
		Ehrlichia_rpt	672..1249	CDD:118064	92/530 (17%)
		DUF4200	689..785	CDD:290574	10/36 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	809..842		4/32 (13%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	859..881		2/21 (10%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1284..1360		14/85 (16%)
		Spc97_Spc98	<1403..1667	CDD:282045	61/285 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2000
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810