Protein Alignment Grip91 and t-Grip128

DIOPT Version :10

• Sequence 1: NP_524919.2
• Gene: Grip91 / 48481
• FlyBaseID: FBgn0001612
• Length: 917
• Species: Drosophila melanogaster
• Sequence 2: NP_729045.1
• Gene: t-Grip128 / 317930
• FlyBaseID: FBgn0052232
• Length: 975
• Species: Drosophila melanogaster
• Alignment Length: 1065
• Identity: 188/1065 - (17%)
• Similarity: 327/1065 - (30%)
• Gaps: 396/1065 - (37%)

  Fly     5 RIAGIDVATNS-TDISNIINEMIICIKGKQMPEVHEKAMDHLSKMIAANSRV---IRDSNMLTER 65
            ||..:.|..:: ..::|:|....||:..||. .:|.:.:|.   :::.|.:.   ||.:  |.|.
  Fly    79 RIENLSVFGDTFNQLANVILNHPICMNHKQR-NIHWRLLDF---VLSVNYKTFVSIRRN--LPEM 137

  Fly    66 ECVQKIMKLLSARNKKEEGKTV--SDHFNELYRKLTLTKCDPHMRHSLMTHLLTMTDNSDAEKAV 128
            |  ||...:|.|.....|...|  .|..|        |||.......|: |..:....|..:|..
  Fly   138 E--QKRKNILEALQMATESSQVDPKDKNN--------TKCVADTEDQLI-HKKSQKPKSPRKKLT 191

  Fly   129 ASEDPRTQCDNLTQILVSR---LNSISSSI----------ASLNEMGVVNGNGVGAAAVTGAAAV 180
            ..:..|. ||.:..:..|:   |:::.|.|          :..|....:|
  Fly   192 PDQIQRL-CDEIRDLTSSKYGSLHTVRSQIPMEQSKPLDTSDYNYSRELN--------------- 240

  Fly   181 TGAAAVTGAAAVTGAAASHSYDATQSSIGLRKQSLPNYLDATKMLPESRHDIVMSAIYSFTGVQG 245
            .|..||.....:.||......:..|:.....|.:|.::
  Fly   241 LGKVAVKENFTIKGAKMELELNVVQNKPSAEKPALVDF--------------------------- 278

  Fly   246 KYLKKDVVTGRFKLDQQNIKFLTTGQAGMLLRLS------ELGYYHDRVVKFSDVSTGFNAIGSM 304
                       ||           .::.||.|:.      ::..|:...:..|:...|:..|...
  Fly   279 -----------FK-----------NESDMLYRIQTNWWQVDISVYNQAHILASNFCQGYADILIF 321

  Fly   305 ----GQALISKLKEELANFHGQVAMLHDEMQRFRQASVNGIANKGKKDSGPDAGDEMTLFKL--- 362
                .||.|.||.||    |    .|..|:.....||.|..:.|...|:.....||.....|
  Fly   322 QLWESQASIRKLSEE----H----QLLSELIVLFFASANCRSFKILNDNWEFRADEPLTCALKQL 378

  Fly   363 -----LAWYIKPLHRMQWLTKIADACQVK------------------------------------ 386
                 |...||.|.:|:.|.::.:...||
  Fly   379 QEGPHLGEIIKSLKQMRHLRELIETYAVKGIRYDRLKTLTFFSVALRQLLRPVIEFLVHFERRLT 443

  Fly   387 --------------KGGDLAS--TVYDFLDNGNDMVN---------------------KLVEDLL 414
                          ..|.|.:  .:|:...|.|..::                     ||:..|.
  Fly   444 SGLEPATLQHFIETSRGHLETIKLLYELSQNKNQELHSLRSLKTLDTLFTKSSQKTQPKLLRSLS 508

  Fly   415 TAICGPLVR----MISKWILEGGISDMHREF-FVKSIKDVGVDRLWHDKFRLRLPMLPKFVPMDM 474
            .::....||    .:..|...|..:|.|.|| |.|.:.|.          |....:....:..::
  Fly   509 ASLLLHTVRAYCKFLDNWWSTGDFADYHEEFPFEKIVTDE----------RTEYVLRKSLMQTEL 563

  Fly   475 ANKILMTGKSINFLREICEEQGMMKERDELMKVMESSASQIF----SYTPDTSWHAAVETC---- 531
            .|..|        .|.|  ::.:::..|.:..:.:|.....|    ...|:...|.::...
  Fly   564 QNSEL--------FRII--QRHLLESSDGVAILYDSRTISEFHTLHGIEPEIRLHNSLIDAVIGE 618

  Fly   532 ---YQ----QTSKHVLDIMVGPHKL--LDHLHGMRRYLLLGQGDFISILIENMK----------N 577
               ||    :.|.:|.||:   .:|  .|| .|:||.       |.|..:|...          |
  Fly   619 IAPYQIKAIEASHYVPDIL---QQLQSTDH-DGIRRL-------FYSFHMETRPDPRKPAGHSIN 672

  Fly   578 ELER---------PGLDIYANDLTSMLDSALRCTNA-------QYDDPDILNHLDVIVQRPFNGD 626
            ||.|         |..:|.:.:...:|:...|..|:       ::....::.||..:.
  Fly   673 ELLRNFLTCADYTPITEIISQEFQRLLNRRTRLVNSYISGLLQEFQGYKVVRHLRSVF------- 730

  Fly   627 IGWN-------------IISLQYIVHGPLAAMLESTMP----------TYKVLFKPLWRMKHMEF 668
            :.||             .:..:::|        |:|..          |...:||......|.||
  Fly   731 LLWNYDHFRSEFEFFFEFLRRKHLV--------EATNKLKHIVLCQDFTLGHMFKVCVTEAHPEF 787

  Fly   669 V---------LSMKIWKEQMGNAKALRTMKSEIGKASHRLNLFTSEIMHF--IHQMQYYVLFEVI 722
            :         |:..|.::||....:...:...:..:.:|||       |.  .|..:|..||:.:
  Fly   788 ICLRVRNDTLLNRIISQQQMDMMNSCFRLLLNLNFSHYRLN-------HLPPFHYCKYERLFKAL 845

  Fly   723 ECNWVELQKKMQKATTLDEILEAHEKFLQTILVGCFVSNKASVEHSLEVVYENIIELEKWQSSFY 787
                                     :.:|..|:..|   :..:.|..: ::..:..|:.:.|
  Fly   846 -------------------------RSIQISLISVF---EEHLSHPCK-LFRKMQNLDSYNS--- 878

  Fly   788 KDCFKELNARKELSKIVEKSEKKGVYGLTNKMILQRDQEA----------KIFAEKMDIACRGLE 842
                 |||   |.:.:.:....:.::||..:..|..:|.|          |:|..:.:..    .
  Fly   879 -----ELN---EFTSLTQLRRNQEIFGLHIRKYLLEEQFACSLPEILTLSKVFCLRWETT----R 931

  Fly   843 VIATDY--EKAVSTF-----LMSLN 860
            .:..:|  :||.|||     |:.||
  Fly   932 ALVDEYRSQKATSTFERRYKLLRLN 956

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grip91	NP_524919.2	GCP_N_terminal	230..544	CDD:465456	70/424 (17%)
		GCP_C_terminal	549..880	CDD:461187	69/391 (18%)
t-Grip128	NP_729045.1	GCP5_NTD	10..121	CDD:454848	11/45 (24%)