Protein Alignment Grip91 and Tubgcp3

DIOPT Version :10

• Sequence 1: NP_524919.2
• Gene: Grip91 / 48481
• FlyBaseID: FBgn0001612
• Length: 917
• Species: Drosophila melanogaster
• Sequence 2: XP_063131531.1
• Gene: Tubgcp3 / 306599
• RGDID: 1305726
• Length: 929
• Species: Rattus norvegicus
• Alignment Length: 907
• Identity: 280/907 - (30%)
• Similarity: 459/907 - (50%)
• Gaps: 125/907 - (13%)

  Fly    11 VATNSTDISNIINEMIIC-IKGKQMPEVHEKAMDHLSKMIAAN--SRVIRDSNMLTERECVQKIM 72
            :||......|::.:.:.| |.|:...:|.:: .....::|.:|  ..|.||..::.|     ||.
  Rat     1 MATPDQKSPNVLLQNLCCRILGRSEADVAQQ-FQFAVRVIGSNFAPTVERDEFLVAE-----KIK 59

  Fly    73 KLLSARNKKEEGKTVSDHFNELYRKLTLTKCDPHM------RHSLMTHLLTMTDNSDAEKAVASE 131
            |.| .|.::|....:   |:||:|||       |.      :.|::..||.:           ||
  Rat    60 KEL-IRQRREADAAL---FSELHRKL-------HSQGVLKNKWSILYLLLNL-----------SE 102

  Fly   132 DPRTQCDNLT-------QILVSRLNS------------ISSSIASLNEMGVVNGNGVGAAAVTGA 177
            |||.|...:|       |.|....:|            ::....|....|.:..:|:.:..:.|
  Rat   103 DPRKQASKVTSYASLFAQALPRDAHSTPYYCARPQTLPLNYQDRSTQSSGSLGSSGISSIGMCG- 166

  Fly   178 AAVTGAAAVTGAAAVTGAAASHSYDATQSSIGLRKQ---------------------SLPNYLDA 221
                    ::|...|.......|:.|.....|||:|                     :.||.|
  Rat   167 --------LSGPTPVQPFLPGQSHQAPGVGDGLRQQLGPRLAWTLTGNQPSQTPTSKAFPNAL-- 221

  Fly   222 TKMLPESRHD-------------IVMSAIYSFTGVQGKYLKKDVVTGRFKLDQQNIKFLTTGQAG 273
            ::.|..||.:             :|...:|.|.|:.||.:|.......:|::.:  ..|:.....
  Rat   222 SRNLTRSRREGDPGGTSEVTEAALVRDILYVFQGIDGKNIKMSSTENCYKVEAK--ANLSKSLRD 284

  Fly   274 MLLRLSELGYYHDRVVKFSDVSTGFNAIGSMGQALISKLKEELANFHGQVAMLHDEMQRFRQASV 338
            ..:||:|||:.|:::.|::|..:...:.|.:||:..:.|.:||..::..:::||.::|.
  Rat   285 TAVRLAELGWLHNKIRKYADQRSLDRSFGLVGQSFCAALHQELKEYYRLLSVLHSQLQL------ 343

  Fly   339 NGIANKGKKDSGPDAGDE--MTLFKLLAWYIKPLHRMQWLTKIADACQVKKGGDLASTVYDFLDN 401
                   :.|.|.:.|.|  :||.:||.|...|..|::.|..:.|.||.:|||:|||.|:.:...
  Rat   344 -------EDDQGVNVGLESSLTLRRLLVWTYDPKIRLKTLAALVDHCQGRKGGELASAVHAYTKT 401

  Fly   402 GNDMVNKLVEDLLTAICGPLVRMISKWILEGGISDMHREFFVKSIKDVGVDRLWHDKFRLRLPML 466
            |:..:..||:.:|:.:..|::..:.:||.:|.:.|.:.||||.|...|..|||||||:.||..|:
  Rat   402 GDPYMKSLVQHILSLVSHPVLSFLYRWIYDGELEDTYHEFFVASDPTVKTDRLWHDKYTLRKSMI 466

  Fly   467 PKFVPMDMANKILMTGKSINFLREICEEQGMMKERDELMKVMES--SASQIFSYTPDTSWHAAVE 529
            |.|:.||.:.|:|:.|||||||.::|.:|....:...:.|..||  .|:.:|: ..:.::...::
  Rat   467 PSFITMDQSRKVLLIGKSINFLHQVCHDQTPTTKMIAVTKSAESPRDAADLFT-DLENAFQGKID 530

  Fly   530 TCYQQTSKHVLDIMVGPHKLLDHLHGMRRYLLLGQGDFISILIENMKNELERPGLDIYANDLTSM 594
            ..|.:|||::||::...:.||:|:..|||||||||||||..|::.:|.||.||...:|.::||.:
  Rat   531 AAYFETSKYLLDVLNRKYSLLEHMQAMRRYLLLGQGDFIRHLMDLLKPELVRPATTLYQHNLTGI 595

  Fly   595 LDSALRCTNAQYDDPDILNHLDVIVQRPFNGDIGWNIISLQYIVHGPLAAML-ESTMPTYKVLFK 658
            |::|:|.||||:|.|:||..|||.:.....||.||::.||.|.|.||:|.:. ...|..|..:|.
  Rat   596 LETAVRATNAQFDSPEILKRLDVRLLEVSPGDTGWDVFSLDYHVDGPIATVFTRECMSHYLRVFN 660

  Fly   659 PLWRMKHMEFVLSMKIWKEQMGNAKALRTMKSEIGKASHRLNLFTSEIMHFIHQMQYYVLFEVIE 723
            .|||.|.||::|: .|.|..|.|||.||.| .|.....|:.::..||::|||||||||:.|||:|
  Rat   661 FLWRAKRMEYILT-DIRKGHMCNAKLLRNM-PEFSGVLHQCHILASEMVHFIHQMQYYITFEVLE 723

  Fly   724 CNWVELQKKMQKATTLDEILEAHEKFLQTILVGCFV-SNKASVEHSLEVVYENIIELEKWQSSFY 787
            |:|.||..::|:|..||.|:.|||.||.||...|.: ||...:.:.|..|::.||||:..|.:.|
  Rat   724 CSWDELWNRVQQAQDLDHIIAAHEAFLDTITSRCLLDSNSRVLLNQLRAVFDQIIELQNAQDTMY 788

  Fly   788 KDCFKELNARKELSKIVEKSEKKGVYGLTNKMILQRDQEAKIFAEKMDIACRGLEVIATDYE 849
            :...:||..|.:..:..::.|.:|.:|:|.....:.::..:.|.:.:...|..|.::...|:
  Rat   789 RAALEELQRRLQFEEKKKQRETEGQWGVTAAEEEEENKRIREFQDSIPKMCSQLRILTHFYQ 850

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grip91	NP_524919.2	GCP_N_terminal	230..544	CDD:465456	99/330 (30%)
		GCP_C_terminal	549..880	CDD:461187	124/303 (41%)
Tubgcp3	XP_063131531.1	None