Protein Alignment Grip91 and alp4

DIOPT Version :10

• Sequence 1: NP_524919.2
• Gene: Grip91 / 48481
• FlyBaseID: FBgn0001612
• Length: 917
• Species: Drosophila melanogaster
• Sequence 2: NP_596044.1
• Gene: alp4 / 2540392
• PomBaseID: SPBC365.15
• Length: 784
• Species: Schizosaccharomyces pombe
• Alignment Length: 556
• Identity: 121/556 - (21%)
• Similarity: 227/556 - (40%)
• Gaps: 104/556 - (18%)

  Fly   384 QVKKGGDLASTVYDFLDN--GNDMVNKLVEDLLTAICGPLVRMISKWILEGGISDMHREFFVKSI 446
            :|.|||.:.|.:.:.|..  |:.:..|::..||.....|..:|:::||..|.::|.:.||.:|..
pombe   251 KVCKGGQVISFLTESLTKYAGDPVARKILTYLLREASRPYTKMLNEWIHLGLVNDPYDEFMIKIH 315

  Fly   447 KDVG--------VDRLWHDKFRLRLPMLPKFVPMDMANKILMTGKSINFLREICEEQGMMKERDE 503
            |.:.        .|..|..::.:|...:|..: :|:.||:|..||.:|.:.| |.     |..:.
pombe   316 KGITSMQLDEDYTDEYWEKRYVIREDQVPPQL-LDLQNKVLFAGKYLNVVLE-CR-----KGVNN 373

  Fly   504 L--MKVMESSASQIF--SYTPDTSWHAAVETCYQQTSKHVLDIMVGPHKLLDHLHGMRRYLLLGQ 564
            |  :...:.:.:|:.  |...|.::...:...|...::.:|.::.....|..||:.::.|..|.|
pombe   374 LASLNAKDDTQNQLLWPSTFDDDNFTLNIMNAYVYANESLLQLLQSSQSLYAHLYSLKHYFFLDQ 438

  Fly   565 GDFISILIENMKNELERPGLDIYANDLTSMLDSALR-------------CTNAQYDDPDILNHLD 616
            .||.:..::|.::||.:|...|....|.|.||.|||             ....:.:...:::.|.
pombe   439 SDFFTTFLDNAQHELRKPAKYISITKLQSQLDLALRQPGTITATDPHKEYVTVEVNQTSLIDWLM 503

  Fly   617 VIVQ------------------------------RPFNG----------------DI-GWNIISL 634
            .||.                              |.|..                || |:..:.|
pombe   504 HIVSISGLEEGTSSQGNEVWNESITKQADVGNETRNFESEHNRSTQGTSKVGSDKDINGFETMQL 568

  Fly   635 QYIVHGPLAAML-ESTMPTYKVLFKPLWRMKHMEFVLSMKIWKEQMGNAKALRTMKSEIGKASHR 698
            .|.|..||:.:| ...:..|::||:....::|:|..|.....:....:|..|.:..::|.:....
pombe   569 CYKVPFPLSLILSRKAIIRYQLLFRYFLLLRHVEMQLENSWVQHSKNSAWRLNSSNAKIEQWKRN 633

  Fly   699 LNLFTSEIMHFIHQMQYYVLFEVIECNWVELQKKMQKATTLDEILEAHEKFLQTILVGCFVSNKA 763
            ..|..:.::.|:.::.||...||||.:|.:...:::.|.|:|.:::.|..||.|.|..|.::|.
pombe   634 SWLLRTRMLSFVQKIIYYTTSEVIETHWGKFMGELENARTVDNLMQEHIDFLDTCLKECMLTNS- 697

  Fly   764 SVEHSLEVVYENIIELEKWQSSFYKDCFKELNARKELSK---IVEKSEKKGVYGLTNKM--ILQR 823
                          .|.|.||.....|....:.....::   ::|.||:....|..:||  ||:|
pombe   698 --------------RLLKVQSKLLNTCAMFASYTSTFTRSLYLLENSEESFDEGRMDKMEEILRR 748

  Fly   824 DQEAKIFAEKMDIACRGLEVIATDYEKAVSTFLMSL 859
            .:::  |:..:..........|:....|:.:.:|.|
pombe   749 YEDS--FSRHLKSLVNACNYFASTETAALLSLVMKL 782

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grip91	NP_524919.2	GCP_N_terminal	230..544	CDD:465456	40/173 (23%)
		GCP_C_terminal	549..880	CDD:461187	81/377 (21%)
alp4	NP_596044.1	GCP_N_terminal	72..367	CDD:465456	32/117 (27%)
		GCP_C_terminal	425..782	CDD:461187	79/373 (21%)