Protein Alignment Grip91 and LOC1276259

DIOPT Version :10

• Sequence 1: NP_524919.2
• Gene: Grip91 / 48481
• FlyBaseID: FBgn0001612
• Length: 917
• Species: Drosophila melanogaster
• Sequence 2: XP_061505472.1
• Gene: LOC1276259 / 1276259
• VectorBaseID: AGAMI1_013802
• Length: 914
• Species: Anopheles gambiae
• Alignment Length: 750
• Identity: 161/750 - (21%)
• Similarity: 314/750 - (41%)
• Gaps: 166/750 - (22%)

  Fly   228 SRHDIVMSAIYS-FTGVQGKYL--KKDVVT----GRFKLDQQNIKFLTTGQAGMLLRLSELGYYH 285
            |:..||:..:.: ..|::|..:  :|...|    |...::.|....||.....|::.:..|...:
Mosquito   240 SQEPIVLKEVLNCLIGIKGTLITPRKGATTLDPDGALAVEFQLSNQLTESCRDMVVEVLPLAANY 304

  Fly   286 DRVVKF---SDVSTGFNAIGSMGQALISKLKEELANFHGQVAMLHDEMQRFRQASVNGIANKGKK 347
            ..|..|   :.|:.|    |.:.|||.|.||..:.:::..:|.|.|  .|.|:.
Mosquito   305 SAVQSFIEGASVTEG----GVVLQALRSVLKTIMTDYYLSIAQLDD--LRCRRG----------- 352

  Fly   348 DSGPDAGDEMTLFKLLAWYIKPLH-RMQWLTKIADACQVK----KGGDLASTVYDFL--DNGNDM 405
                     ::|.:|:. ::||:: .|:.|.  |...:::    :||.:.|.::|.:  .:|.:.
Mosquito   353 ---------LSLQRLIQ-FLKPVYPTMEELA--ATVSEIRRSNARGGQVLSLLHDRITAKSGTNH 405

  Fly   406 VNKLVEDLLTAICGPLVRMISKWILEGGISDMHREFFV-KSIKDVGVDRL---WHDKFRLRLPML 466
            ..|::..|:.:...|.:.|:..||..|.|:|..:|||: .|..::..:.|   |..::.:|...:
Mosquito   406 AQKVLVHLVESAAAPFMEMLELWIYRGVINDPQQEFFIDHSSMELTENELVDYWEKQYTIRNEKV 470

  Fly   467 PKFVPMDMANKILMTGKSINFLREIC---EEQ---------GMMKERDELMKVMESSAS-----Q 514
            |.|:... |:.||.|||.:|.:| :|   |.|         |......:|:....::|.     :
Mosquito   471 PCFLAKH-ADIILRTGKYLNVVR-VCGGAEFQPGNANGGGGGGATTTTDLLNASSATARTTTAVK 533

  Fly   515 IFSYTP-DTSWHAAVETCYQQTSKHVLDIMVGPHKLLDHLHGMRRYLLLGQGDFISILIENMKNE 578
            ...|.. |.|:...:|..|...|..:|::::..:.|:..|..::||.||.|||||:..::.::.:
Mosquito   534 RLQYAHFDQSYLDEIEEAYNFASSSLLNLIMNKYDLMGRLLSVKRYFLLQQGDFITEFMDAVEED 598

  Fly   579 LERPGLDIYANDLTSMLDSALRCTNAQYDD------------------PDILNHLDVIVQRPFNG 625
            |.:....::...|.::||..|..::|:||:                  ..|:|:.|..|....:.
Mosquito   599 LRKSVDTLHPIRLANLLDVTLGLSSAKYDEYHDDLKTMLLPYGIVTQISKIVNNEDAFVDTLSDT 663

  Fly   626 D--IGWNIISLQYIVHGPLAAMLES-TMPTYKVLFKPLWRMKHMEFVLSMKIWKEQMGNAKALRT 687
            .  .|....:..|....|::.:|.. |:..|:::|:.|:.:|::|.:| .::|   :.|.:   |
Mosquito   664 SQLKGVECFTFTYKAQWPVSIVLNLWTISKYQMIFRQLFYLKYVERIL-CRVW---IANNE---T 721

  Fly   688 MKSEIGKASHRLNLFT--SEIMHFIHQMQYYVLFEVIECNWVELQKKMQKATTLDEILEAHEKFL 750
            .:.....|....:.||  .:::..|...:.|::.||||.||....:.|::...:|::|..|:.||
Mosquito   722 RQFAPNPAKLYRSAFTLRQKMLIAIQSFESYMMIEVIEPNWHIFYQNMKQVKNIDDVLNYHQDFL 786

  Fly   751 QTILVGCFVSNKASVEHSLEVVYENIIELEKWQSSFYKDCFKELNARKELSKIVEKSEKKGVYGL 815
            ...|..|.::     |..|.....|:..:          |.|       ....:.:|::..|...
Mosquito   787 DQCLKNCMLT-----EPDLLKPIINLCNI----------CIK-------FCDFLAESQRHFVDAE 829

  Fly   816 TNKMILQRDQEAKIFAEKMDIACRGLEVIATDYEKAVSTF--------------------LMSL- 859
            ...|:...| :..:.:|             :|||:..:|.                    ||:|
Mosquito   830 LTCMLASGD-DCSLSSE-------------SDYEQTATTMAPTETFSERVEQFRHDFTDQLMTLL 880

  Fly   860 --------NSSDDPNLQLFGTRLDFNEYYKKRDTN 886
                    .|:.:..:.|. .|::||.||.:.:.|
Mosquito   881 RKIADVATLSTSERFINLI-YRINFNSYYSETNEN 914

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grip91	NP_524919.2	GCP_N_terminal	230..544	CDD:465456	79/352 (22%)
		GCP_C_terminal	549..880	CDD:461187	78/382 (20%)
LOC1276259	XP_061505472.1	None