Protein Alignment Grip91 and tubgcp3

DIOPT Version :10

• Sequence 1: NP_524919.2
• Gene: Grip91 / 48481
• FlyBaseID: FBgn0001612
• Length: 917
• Species: Drosophila melanogaster
• Sequence 2: NP_001116269.1
• Gene: tubgcp3 / 100101728
• XenbaseID: XB-GENE-490983
• Length: 906
• Species: Xenopus tropicalis
• Alignment Length: 943
• Identity: 296/943 - (31%)
• Similarity: 491/943 - (52%)
• Gaps: 135/943 - (14%)

  Fly    20 NIINEMIIC-IKGKQMPEVHEKAMDHLSKMIAAN--SRVIRDSNMLTERECVQKIMKLLSARNKK 81
            |::.:.:.| |.||...:|.:: ..:..::|.:|  ..|.||..::.|     ||.|....:.::
 Frog    10 NVLLQNLCCRILGKGEADVAQQ-FQYAVRVIGSNFAPTVERDEFLVAE-----KIKKEFVRQRRE 68

  Fly    82 EEGKTVSDHFNELYRKLT---LTKCDPHMRHSLMTHLLTMTDNSDAEKAVASEDPRTQCD----- 138
            .:|..    |:||:|||.   :.|    .|.|::..||::           |||||.|.:
 Frog    69 ADGAL----FSELHRKLQSQGVLK----NRWSVLYLLLSL-----------SEDPRKQPNKTSSY 114

  Fly   139 ------------NLTQILVSRLNSISSSIASLNEMGVVNGNGVGAAAV--TGAAAVTGAAAVTGA 189
                        :.|....:|..|:..|....|.....|...:|::.:  .|..|:.|.   |..
 Frog   115 AALFAQALPRDAHSTPYYYARPQSLQLSYQDRNVQCAQNAASMGSSGIGSIGMYALNGP---TPQ 176

  Fly   190 AAVTGAAASHSY------DATQSSIGLR------------KQS-----LPNYLDATKMLPESRHD 231
            :.:.|    .||      ||.:..:|.|            :||     |||  ..::.:|.:|.:
 Frog   177 SIIQG----QSYQTPNMGDALRQQLGSRLAWTLAAGQQPSQQSTTTKGLPN--TVSRNVPRTRRE 235

  Fly   232 -------------IVMSAIYSFTGVQGKYLKKDVVTGRFKLD-----QQNIKFLTTGQAGMLLRL 278
                         :|...:|.|.|:.||::|.......:|:|     .:::|.:|:       :|
 Frog   236 GDSSGSVEITETALVRDLLYVFQGIDGKFIKMCNSENCYKVDGKVALSKSLKDITS-------KL 293

  Fly   279 SELGYYHDRVVKFSDVSTGFNAIGSMGQALISKLKEELANFHGQVAMLHDEMQRFRQASVNGIAN 343
            :|||:.|:::.|::|..:...|.|.:||:..:.|.:||..::..:::||.::|
 Frog   294 AELGWLHNKIRKYTDQRSLDRAFGLVGQSFCAALHQELKEYYRLLSVLHSQLQ------------ 346

  Fly   344 KGKKDSGPDAGDE--MTLFKLLAWYIKPLHRMQWLTKIADACQVKKGGDLASTVYDFLDNGNDMV 406
             .:.|.|.:.|.|  :||.:||.|...|..|::.|..:.|.||.:|||:|||.|:.:...|:..:
 Frog   347 -VEDDQGVNLGMESNLTLRRLLVWTYDPKIRLKTLAALVDHCQGRKGGELASAVHAYTKTGDPYM 410

  Fly   407 NKLVEDLLTAICGPLVRMISKWILEGGISDMHREFFVKSIKDVGVDRLWHDKFRLRLPMLPKFVP 471
            ..||:.:|..:..|::..:.:||.:|.:.|.:.||||.|...|..|||||||:.||..|:|.|:.
 Frog   411 RSLVQHILGLVSHPILNFLYRWIYDGELEDTYHEFFVASDPMVKTDRLWHDKYSLRKSMIPSFMT 475

  Fly   472 MDMANKILMTGKSINFLREICEEQGMMKERDELMKVMESS-----ASQIFSYTPDTSWHAAVETC 531
            ||.:.|:|:.|||||||.::|.:|   ....:.|.|.:|:     |:.:|: ..:.::.:.::..
 Frog   476 MDQSRKVLLIGKSINFLHQVCHDQ---TPATKTMAVGQSAESPKDAADLFT-DLENAFQSKIDAA 536

  Fly   532 YQQTSKHVLDIMVGPHKLLDHLHGMRRYLLLGQGDFISILIENMKNELERPGLDIYANDLTSMLD 596
            |..|||::||::...:.||:|:..|||||||||||||..|::.:|.||.||...:|.::||.:|:
 Frog   537 YFDTSKYLLDVLNKNYNLLEHMQAMRRYLLLGQGDFIRHLMDLLKPELVRPATTLYQHNLTGILE 601

  Fly   597 SALRCTNAQYDDPDILNHLDVIVQRPFNGDIGWNIISLQYIVHGPLAAML-ESTMPTYKVLFKPL 660
            :|:|.||||:|:|:||..|||.:.....||.||::.||.|.|.||:|.:. ...|..|..:|..|
 Frog   602 TAVRATNAQFDNPEILKRLDVRLLEVSPGDTGWDVFSLDYHVDGPIATVFTRECMSHYLRVFNFL 666

  Fly   661 WRMKHMEFVLSMKIWKEQMGNAKALRTMKSEIGKASHRLNLFTSEIMHFIHQMQYYVLFEVIECN 725
            ||.|.||::|: .|||..|.|||.|::| .|:....|:.::..||::|||||||||:.|||:||:
 Frog   667 WRAKRMEYILT-DIWKGHMCNAKLLKSM-PELSGVLHQCHILASEMVHFIHQMQYYITFEVLECS 729

  Fly   726 WVELQKKMQKATTLDEILEAHEKFLQTILVGCFV-SNKASVEHSLEVVYENIIELEKWQSSFYKD 789
            |.||..|:.:|..||.|:.||:.||.||:..|.: |...::.:.|..|::.|||.:..|.:.|:.
 Frog   730 WDELWNKVLQAQDLDHIIAAHDVFLDTIISRCLLDSESRALLNQLRAVFDQIIEFQNAQDALYRA 794

  Fly   790 CFKELNARKELSKIVEKSEKKGVYGLTNKMILQRDQEAKIFAEKMDIACRGLEVIATDYEKAVST 854
            ..:||..|.:..:..::...:|.:|:|.....:.::..:.|.|.:......|.::...|:..|..
 Frog   795 ALEELQLRLQFEERKKERASEGQWGVTAAEEEEENKRVQEFQESIPKMRSQLRILTHFYQGIVEQ 859

  Fly   855 FLMSLNSSDDPNLQLFGTRLDFNEYYKKRDTNL 887
            ||:.|.:|.|.:|:....||||||:||.|:..|
 Frog   860 FLVLLTTSTDESLRFLSFRLDFNEHYKAREPRL 892

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grip91	NP_524919.2	GCP_N_terminal	230..544	CDD:465456	101/338 (30%)
		GCP_C_terminal	549..880	CDD:461187	133/332 (40%)
tubgcp3	NP_001116269.1	GCP_N_terminal	250..550	CDD:465456	101/323 (31%)
		GCP_C_terminal	554..885	CDD:461187	133/332 (40%)