Protein Alignment Dip-B and NPEPL1

DIOPT Version :9

• Sequence 1: NP_001287316.1
• Gene: Dip-B / 48450
• FlyBaseID: FBgn0000454
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_078939.3
• Gene: NPEPL1 / 79716
• HGNCID: 16244
• Length: 523
• Species: Homo sapiens
• Alignment Length: 449
• Identity: 116/449 - (25%)
• Similarity: 183/449 - (40%)
• Gaps: 83/449 - (18%)

  Fly    90 RSMEKVLKAGFHTPLLFVPKVKRFPEV--ELCTVLGALEQLYVPIQLREAGTLKDPRVTTLSVQI 152
            |.:...|..|.|..::.|.:.   |||  ..|.:..|.     |:....:|..:.....|::|:.
Human    97 RLVRTCLPPGAHRCIVMVCEQ---PEVFASACALARAF-----PLFTHRSGASRRLEKKTVTVEF 153

  Fly   153 -----DDPRAEAIFQEAL--ILEAGRFVARDIGVGDPERMTPIQVEKYIKPLFDKLNV--NVISD 208
                 |:...|....:.|  ..:..|..||.:.....|..|...:|: |..:..:|.:  .:|.|
Human   154 FLVGQDNGPVEVSTLQCLANATDGVRLAARIVDTPCNEMNTDTFLEE-INKVGKELGIIPTIIRD 217

  Fly   209 TQVLQKEYPLFAAVNRAADAVERHRGRIIFLEYKPPKPARKTLMLVGKGVTYDTGGADIKAGGVM 273
            .::..:.:.....|.:||    .|...:..|.: .|..|.:|:..||||:.|||||..||....|
Human   218 EELKTRGFGGIYGVGKAA----LHPPALAVLSH-TPDGATQTIAWVGKGIVYDTGGLSIKGKTTM 277

  Fly   274 AGMSRDKCGAAAVAG-FMQVVSQLQPDDIHVVAALCMVRNSVGEECYVADEVITSRAGLHVRIGN 337
            .||.||..|||||.| |...:.|...|::|  |..|:..||||......|::....:|..|.|.|
Human   278 PGMKRDCGGAAAVLGAFRAAIKQGFKDNLH--AVFCLAENSVGPNATRPDDIHLLYSGKTVEINN 340

  Fly   338 TDAEGRMCMTDAL---CRMKELVVEQNLPDPHLFTIATLTGHAFISAGEGQSIAIDNSVAHREDH 399
            ||||||:.:.|.:   |:        :|....:..:|||||...|:.|:..:..:.||.   |..
Human   341 TDAEGRLVLADGVSYACK--------DLGADIILDMATLTGAQGIATGKYHAAVLTNSA---EWE 394

  Fly   400 ARRLQAAGQAFGEPFEVSILRP----SDFSFNAGKVIGEDLVQANNAPSVRTPRGHQVPAAFMIK 460
            |..:: ||:..|:.....:..|    |:|: :|...:...:...:|:||       .....|:..
Human   395 AACVK-AGRKCGDLVHPLVYCPELHFSEFT-SAVADMKNSVADRDNSPS-------SCAGLFIAS 450

  Fly   461 ASGLDKHGLDSMLPIKYTHIDIA---------------------GSAGEHPAMPTAAPL 498
            ..|.|..|:       :.|:|||                     |.|.|.|.:...:||
Human   451 HIGFDWPGV-------WVHLDIAAPVHAGERATGFGVALLLALFGRASEDPLLNLVSPL 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dip-B	NP_001287316.1	Peptidase_M17	58..502	CDD:238247	116/449 (26%)
NPEPL1	NP_078939.3	Peptidase_M17	35..487	CDD:238247	110/432 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0260
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D562530at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1683
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.850