DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dip-B and Npepl1

DIOPT Version :9

Sequence 1:	NP_001287316.1	Gene:	Dip-B / 48450	FlyBaseID:	FBgn0000454	Length:	508	Species:	Drosophila melanogaster
Sequence 2:	XP_006235750.1	Gene:	Npepl1 / 311671	RGDID:	1311351	Length:	524	Species:	Rattus norvegicus

Alignment Length:	451	Identity:	120/451 - (26%)
Similarity:	185/451 - (41%)	Gaps:	87/451 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    90 RSMEKVLKAGFHTPLLFVPKVKRFPEV--ELCTVLGALEQLYVPIQLREAGTLKDPRVTTLSVQI 152
            |.:...|..|.|..:|.|.:.   |||  ..|.:..|.     |:....:|..:.....|:.|:.
  Rat    97 RLVRTCLPPGTHRCILMVCEQ---PEVFASACALARAF-----PLFTHRSGASRRTEKRTVMVEF 153

  Fly   153 -----DDPRAEAIFQEAL--ILEAGRFVARDIGVGDPERMTPIQVEKYIKPLFDKLNV--NVISD 208
                 |:...|....:.|  ..|..|..||.:.....|..|.|.:|: |..:..:|.:  .:|.|
  Rat   154 FLVGQDNGPVEVSTLQCLTNATEGVRLAARIVDTPCSEMNTDIFLEE-ISQVGRELGITPTIIRD 217

  Fly   209 TQVLQKEYPLFAAVNRAADAVERHRGRIIFLEYKPPKPARKTLMLVGKGVTYDTGGADIKAGGVM 273
            .|:..|.:.....|.:||    .|...:..|.: .|..|.:|:..||||:.|||||..||....|
  Rat   218 EQLKTKGFGGIYGVGKAA----LHPPALAVLSH-TPDGATQTIAWVGKGIVYDTGGLSIKGKTTM 277

  Fly   274 AGMSRDKCGAAAVAG-FMQVVSQLQPDDIHVVAALCMVRNSVGEECYVADEVITSRAGLHVRIGN 337
            .||.||..||||:.| |...:.|...|::|  |..|:..|:||......|::....:|..|.|.|
  Rat   278 PGMKRDCGGAAAILGAFRAAIKQGFKDNLH--AVFCLAENAVGPNATRPDDIHLLYSGKTVEINN 340

  Fly   338 TDAEGRMCMTDAL---CR--MKELVVEQNLPDPHLFTIATLTGHAFISAGEGQSIAIDNSVAHRE 397
            ||||||:.:.|.:   |:  ..:::|:          :|||||...|:.|:..:..:.||.   |
  Rat   341 TDAEGRLVLADGVSYACKDLGADIIVD----------MATLTGAQGIATGKYHAAVLTNSA---E 392

  Fly   398 DHARRLQAAGQAFGEPFEVSILRP----SDFSFNAGKVIGEDLVQANNAPSVRTPRGHQVPAAFM 458
            ..|..:: |||..|:.....:..|    |:|: :|...:...:...:|:||       .....|:
  Rat   393 WEAACVK-AGQKCGDLVHPLVYCPELHFSEFT-SAVADMKNSVADRDNSPS-------SCAGLFI 448

  Fly   459 IKASGLDKHGLDSMLPIKYTHIDIA---------------------GSAGEHPAMPTAAPL 498
            ....|.|..|:       :.|:|||                     |.|.|.|.:...:||
  Rat   449 ASHIGFDWPGV-------WVHLDIAAPVHAGERATGFGVALLLALFGRASEDPLLNLVSPL 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dip-B	NP_001287316.1	Peptidase_M17	58..502	CDD:238247	120/451 (27%)
Npepl1	XP_006235750.1	Peptidase_M17	35..487	CDD:238247	114/434 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0260
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D562530at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820