DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dip-B and SPAC13A11.05

DIOPT Version :9

Sequence 1:	NP_001287316.1	Gene:	Dip-B / 48450	FlyBaseID:	FBgn0000454	Length:	508	Species:	Drosophila melanogaster
Sequence 2:	NP_592993.1	Gene:	SPAC13A11.05 / 2542130	PomBaseID:	SPAC13A11.05	Length:	513	Species:	Schizosaccharomyces pombe

Alignment Length:	508	Identity:	123/508 - (24%)
Similarity:	185/508 - (36%)	Gaps:	115/508 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 AVPNELKATFEEHRK-FDKSFDSSISCFKVPNVD--------QPVVYAPVSELTDYDDVRSYQEA 87
            ||.::.:...|::|: .|:.|::|      |..:        |..|...:.:|.:....:|.:.|
pombe    37 AVRHDKQVFSEDYRQVVDQYFETS------PKKNDIRLFWNTQGFVRLAIVQLEENVSEKSVRSA 95

  Fly    88 AKRSMEKVLKA-----------GFHTPLLFVPKVKRFPEVELCTVLGALEQLYVPIQLR--EAGT 139
            |..: .|:||:           ||       ||         ...|||....| ...||  ....
pombe    96 AAEA-AKILKSNGAKSIAVDGMGF-------PK---------DAALGAALATY-DFSLRRDHLSV 142

  Fly   140 LKDPRVTTLSVQIDDPRAEAI--------------------FQEALILEAGRFVARDIGVGDPER 184
            .:|.:|.........|..|.:                    |:..||..|.:.:||.:.......
pombe   143 YQDEKVVEKENLFTSPAPERLTFQLLSNTSEKKTATAEENAFKVGLIEAAAQNLARSLMECPANY 207

  Fly   185 MTPIQVEKYIKPLF---DKLNVNVISDTQVLQKEYPLFAAVNRAADAVERHRGRIIFLEY----K 242
            ||.:|...:.:.||   .|:.|.|..:..:.:::......||..:|...|      |||.    |
pombe   208 MTSLQFCHFAQELFQNSSKVKVFVHDEKWIDEQKMNGLLTVNAGSDIPPR------FLEVQYIGK 266

  Fly   243 PPKPARKTLMLVGKGVTYDTGGADIKAGGVMAGMSRDKCGAAAVAGFMQVVSQLQ-PDDIHVVAA 306
            ........|.|||||||:|:||..||....|..|..|..|||.:...:..:.||. |  ::.|..
pombe   267 EKSKDDGWLGLVGKGVTFDSGGISIKPSQNMKEMRADMGGAAVMLSSIYALEQLSIP--VNAVFV 329

  Fly   307 LCMVRNSVGEECYVADEVITSRAGLHVRIGNTDAEGRMCMTDALCRMKELVVEQNLPDPHLFTIA 371
            ..:..|..........:||..|.||.|.|.|||||||:.:.||:     ..|........:...:
pombe   330 TPLTENLPSGSAAKPGDVIFMRNGLSVEIDNTDAEGRLILADAV-----HYVSSQYKTKAVIEAS 389

  Fly   372 TLTGHAFISAGEGQSIAIDNSVAHREDHARRLQAAGQAFGE-----PFEVSILRPSDFSFNAGKV 431
            ||||...::.|.    ....:....|:..:.|:.|....|:     ||..:.|:....|.||
pombe   390 TLTGAMLVALGN----VFTGAFVQGEELWKNLETASHDAGDLFWRMPFHEAYLKQLTSSSNA--- 447

  Fly   432 IGEDLVQANNAPSVRTPRGHQVPAAFMIKASGLDKHGLDSMLPIKYTHIDIAG 484
               ||...:.|      .|....||..||.....|       .:.:.|:||||
pombe   448 ---DLCNVSRA------GGGCCTAAAFIKCFLAQK-------DLSFAHLDIAG 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dip-B	NP_001287316.1	Peptidase_M17	58..502	CDD:238247	116/481 (24%)
SPAC13A11.05	NP_592993.1	PepB	14..513	CDD:223338	123/508 (24%)
SPAC13A11.05	NP_592993.1	Peptidase_M17	31..508	CDD:238247	123/508 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0260
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1683
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840